...Jing Gao; Akiko Mizokami; Hiroshi Takeuchi; Aonan Li; Fei Huang; Haruki Nagano; Takashi Kanematsu; Eijiro Jimi; Masato Hirata ABSTRACT Insulin signalling is tightly controlled by various factors, but the exact molecular mechanism remains incompletely understood. We have previously reported...

... unknown. In this study, we have shown that miR-128a is highly expressed in brain and skeletal muscle, and increases during myoblast differentiation. MiR-128a was found to regulate the target genes involved in insulin signaling, which include Insr (insulin receptor), Irs1 (insulin receptor substrate 1...

...-mail: jwoodget@uhnres.utoronto.ca ) © The Company of Biologists Limited 2003 2003 Signal transduction Phosphorylation Wnt signalling Insulin signalling Protein structure-function Glycogen synthase kinase 3 (GSK-3) is a serine/threonine kinase that was first isolated and purified as an enzyme...