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Keywords: Histone acetylation
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Journal Articles
J Cell Sci (2022) 135 (10): jcs259586.
Published: 26 May 2022
... on the viability of adherent tumor cells and decreases their nuclear size. Shear flow promotes histone acetylation in suspended tumor cells, the inhibition of which using one drug suppresses shear-induced nuclear expansion, suggesting that shear stress might increase nuclear size through histone acetylation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (2): jcs259132.
Published: 24 January 2022
... in regulating gene expression. Here, we show that although the SAGA, ADA and CHAT complexes play redundant roles in embryonic gene expression, the insect-specific CHAT complex uniquely regulates expression of a subset of developmental genes. We also identify a substantial decrease in histone acetylation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (1): jcs236489.
Published: 9 January 2020
... in the vicinity of the food vacuole is important for its function in Plasmodium falciparum . Malaria Plasmodium falciparum GCN5 Histone acetyltransferase Histone acetylation Cysteine protease Protein processing ChIP sequencing ChIP seq Epigenetics is one centrally important mechanism...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (2): jcs214072.
Published: 16 January 2019
... reported to be dispensable for viability, here, we find that Chiffon is required for both histone acetylation and viability in flies. Surprisingly, we show that chiffon is a dicistronic gene that encodes distinct Cdc7- and CHAT-binding polypeptides. Although the Cdc7-binding domain of Chiffon...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (24): 4213–4224.
Published: 15 December 2017
...). Bottom: Relative size of the reporter gene array over time as measured on the microscopy images. (C) Western blot of cells treated with (+) and without (−) SAHA. Treatment with SAHA (2 µM) for 24 h led to an increase of pre-existing histone acetylation. (D) Cell-to-cell heterogeneity of response times...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (11): 2732–2739.
Published: 1 June 2012
... in the absence of HDAC1 ( supplementary material Fig. S4B ,C). These findings provide a functional link between pre-rRNA synthesis and RUNX2-mediated deacetylation of UBF by HDAC1. An important mechanism by which HDACs control gene transcription is the modification of histone acetylation in gene regulatory...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (4): 965–972.
Published: 15 February 2012
... of replication in higher eukaryotes and a means to dissect Orc-dependent and Orc-independent events at origins. * Author for correspondence ( s.cotterill@sgul.ac.uk ) 5 9 2011 © 2012. 2012 Orc DNA replication Origin of replication Gal4 Drosophila S2 cells Histone acetylation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (12): 2041–2048.
Published: 15 June 2011
... regulated by the histone deacetylase Rpd3. * Authors for correspondence ( giovanni.cenci@cc.univaq.it ; dcorona@unipa.it ) 2 3 2011 © 2011. 2011 Telomere Rpd3 Heterochromatin Histone acetylation Histone H3K9 trimethylation HP2 Eukaryotic linear chromosomes have evolved...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (20): 3366–3372.
Published: 15 October 2008
... Limited 2008 2008 Histone acetylation Histone phosphorylation ATAC JIL-1 SU(VAR)3-9 GCN5 ADA2 ...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (9): 1689–1700.
Published: 1 May 2007
...@staff.uni-marburg.de ) * Present address: EMBL, Heidelberg, Germany 14 3 2007 © The Company of Biologists Limited 2007 2007 Drosophila Histone acetylation Histone methylation Histone ubiquitylation Transition protein Protamine CTCF DNA breaks Rad6 UbcD6 RNA polymerase...
Journal Articles
J Cell Sci (2005) 118 (21): 5035–5046.
Published: 1 November 2005
...., Schmid, M., Opravil, S., Mechtler, K., Ponting, C. P., Allis, C. D. and Jenuwein, T. ( 2000 ). Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406 , 593 -599. Rice, J. C. and Allis, C. D. ( 2001 ). Histone methylation versus histone acetylation: new...
Journal Articles
J Cell Sci (2004) 117 (11): 2173–2181.
Published: 1 May 2004
...-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. Mol. Cell Biol. (in press). Trimarchi, J. M. and Lees, J. A. ( 2002 ). Sibling rivalry in the E2F family. Nat. Rev. Mol. Cell. Biol. 3 , 11 -20. Trimarchi, J. M., Fairchild, B., Wen...
Journal Articles
J Cell Sci (2003) 116 (19): 4021–4034.
Published: 1 October 2003
... (e-mail: g44478a@nucc.cc.nagoya-u.ac.jp ) 4 6 2003 © The Company of Biologists Limited 2003 2003 Centromere Alpha-satellite Mammalian artificial chromosome Heterochromatin Histone acetylation Our understanding of the molecular mechanisms that specify the sites...
Journal Articles
J Cell Sci (2002) 115 (24): 4765–4775.
Published: 15 December 2002
... of chromatin compaction,so that chromosomes are cytologically individualized. We investigated chromatin differences between parental chromosomes in Sciara ocellaris and S. coprophila by analyzing histone acetylation modifications in early germ nuclei. We examined germ nuclei from early embryonic stages...
Journal Articles
J Cell Sci (2002) 115 (23): 4597–4605.
Published: 1 December 2002
... and induced changes in DNA methylation and histone acetylation, using in situ hybridisation and confocal 3D imaging. After germinating seeds either in the presence of 5-Azacytidine (5-AC), which leads to DNA hypomethylation, or trichostatin A (TSA), which results in histone hyperacetylation, the architecture...