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Keywords: Hippocampus
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Journal Articles
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Lipid Biology
J Cell Sci (2021) 134 (9): jcs254276.
Published: 11 May 2021
... excitatory synapse formation in vitro and in vivo through motifs at its C-terminal domain. Hippocampus Lipid Palmitate Palmitoyl acyltransferase Palmitoylation Synapse Palmitoylation is a reversible post-translational lipid modification that anchors proteins to specialized membrane...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (7): jcs239756.
Published: 8 April 2020
... of the hippocampus and the astrocyte's proximity to amyloid plaques. To validate our method, we confirmed that the ubiquitous Rpl4 (large subunit ribosomal protein 4) mRNA was present in astrocyte processes as well as in microglia processes immunolabelled for ionized calcium binding adaptor molecule 1 (Iba1; also...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2016) 129 (14): 2852–2864.
Published: 15 July 2016
... and the signaling cascades required for local BDNF translation in dendrites in response to excitatory inputs. Neurotrophins Hippocampus Protein synthesis Pilocarpine Translation of a subset of dendritically localized mRNAs in close proximity to activated synapses is a fundamental mechanism...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (9): 1802–1814.
Published: 1 May 2016
... plays a crucial role in redirecting local Sema3A signaling to retrograde axonal transport, thereby regulating dendritic GluA2 localization and patterning. Hippocampus Semaphorin 3A NGF TrkA PlexA4 Axonal transport Various neurotrophic factors, such as nerve growth factor (NGF...
Journal Articles
J Cell Sci (2016) 129 (7): 1378–1390.
Published: 1 April 2016
... protein for secretion proteins (CAPS1 and CAPS2, also known as CADPS and CADPS2, respectively). CAPS1 is expressed in several brain regions, including the cerebellum, cortex, hippocampus and olfactory bulb ( Sadakata et al., 2006 ; Speidel et al., 2003 ). In hippocampal neurons, CAPS1 is localized...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (2): 281–292.
Published: 15 January 2015
... presynaptic organizers necessary for excitatory and inhibitory presynaptic differentiation, respectively, in the hippocampus. For the establishment of specific synaptic networks, these FGFs must localize to appropriate synaptic locations – FGF22 to excitatory and FGF7 to inhibitory postsynaptic sites. Here...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (24): 5253–5260.
Published: 15 December 2014
... of Biologists Ltd 2014 FRET Hippocampus PI3K PTEN Synaptic plasticity Phosphoinositides (phosphorylated derivatives of phosphatidylinositol) are asymmetrically distributed throughout intracellular compartments and the plasma membrane and, in this fashion, are thought to provide essential...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (12): 2782–2792.
Published: 15 June 2014
.... , Ashley   R. H. ( 1998 ). Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.   Neuroscience   85 , 205 – 216 . 10.1016/S0306--4522(97)00612--X Marx   S. O. , Reiken   S. , Hisamatsu...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (12): 2034–2042.
Published: 15 June 2009
... guidance Hippocampus Semaphorin The ephrins, netrins, Slit proteins and semaphorins are four families of guidance signals that direct the extension of axons and dendrites, and serve as attractive or repellent cues during the establishment of neuronal connections ( Dickson, 2002 ; Goldberg, 2004...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (5): 735–744.
Published: 1 March 2009
... levels. These mice had combined 4.1G and 4.1N protein expression in the hippocampus at 12% of wild-type levels (equivalent to 8-10% of combined GluR1 and GluR4 expression levels). They show a moderate reduction in synaptosomal expression levels of the AMPA receptor subunit GluR1 at 3 weeks of age...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (11): 1869–1875.
Published: 1 June 2008
... protein is an established prerequisite for biological responses to this ligand. Here we show that the inactivation of a conditional Dab1 allele reduces process complexity in correctly positioned neurons in the CA1 region of the mouse hippocampus after birth. Reelin stimulation of cultured hippocampal...
Journal Articles
J Cell Sci (2007) 120 (8): 1358–1370.
Published: 15 April 2007
... cells in the late embryonic and adult hippocampus. Dev. Neurosci. 25 , 257 -272. LoTurco, J. J., Owens, D. F., Heath, M. J., Davis, M. B. and Kriegstein, A. R. ( 1995 ). GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis. Neuron 15 , 1287 -1298. Luk, K. C...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (6): 985–995.
Published: 15 March 2007
... 9 1 2007 © The Company of Biologists Limited 2007 2007 Co-immunoprecipitation Channel coupling Hippocampus Action potential Membrane proteins can be organised into complexes with other proteins. There has been particular focus on the association of effector molecules...
Journal Articles
J Cell Sci (2006) 119 (23): 4986–4993.
Published: 1 December 2006
... are thus likely to underlie the mental retardation induced by mutations of ARHGEF6 and PAK3. * Author for correspondence (e-mail: Bernadett.Boda@medecine.unige.ch ) 21 9 2006 © The Company of Biologists Limited 2006 2006 Alpha-pix Hippocampus Postsynaptic density siRNA...
Journal Articles
J Cell Sci (2005) 118 (16): 3791–3803.
Published: 15 August 2005
... the control of the human GFAP promoter, we tested for synaptic input to identified glial cells in the hippocampus. Electron microscopic inspection identified synapse-like structures with EGFP-positive postsynaptic compartments. Sub-threshold stimulation to Schaffer collaterals resulted in stimulus-correlated...
Includes: Supplementary data
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