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Keywords: Glucose
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Journal Articles
J Cell Sci (2019) 132 (21): jcs222570.
Published: 13 November 2019
.... , Galda , S. N. , Sengupta , S. , Mahoney , S. J. , Howell , J. J. , Molz , L. , Hahm , S. , et al. ( 2019 ). Discovery of small-molecule selective mTORC1 inhibitors via direct inhibition of glucose transporters . Cell Chem Biol.   26 , 1203 - 1213.e13 . 10.1016/j.chembiol...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (4): jcs208629.
Published: 20 February 2018
...Renzhong Li; Tony Wang; Khyati Walia; Bo Gao; Joan C. Krepinsky ABSTRACT Glomerular matrix accumulation is the hallmark of diabetic nephropathy. The metalloprotease ADAM17 mediates high glucose (HG)-induced matrix production by kidney mesangial cells through release of ligands for the epidermal...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2018) 131 (1): jcs208769.
Published: 8 January 2018
... on primary cilium formation. Glucose deprivation significantly increased the number of ciliated cells under both serum-fed and -starved conditions. Glucose deprivation-induced ciliogenesis was suppressed by overexpression of Rheb, an activator of the mammalian target of rapamycin complex-1 (mTORC1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (23): 4411–4423.
Published: 1 December 2016
..., we studied the mechanism of this homeostatic phenomenon in C2C12 myoblasts. Acute (30 min) mitoenergetic dysfunction induced by the mitochondrial inhibitors piericidin A and antimycin A stimulated Glut1-mediated glucose uptake without altering Glut1 (also known as SLC2A1) mRNA or plasma membrane...
Journal Articles
J Cell Sci (2016) 129 (21): 4067–4075.
Published: 1 November 2016
.... In order to get quantitative information about the size of lipid droplets and the shape of mitochondria under growth in glucose and oleate ( Fig. S1A–E ), an in-house script was written in ImageJ ( http://imagej.net/Fiji/Downloads ), which includes a rolling ball algorithm for subtracting the background...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (9): 1492–1502.
Published: 1 May 2010
... by phospholipase C (PLC)-activating receptor agonists or stimulatory glucose concentrations was paralleled by increased PtdIns(4) P levels. In addition, glucose-stimulated cells regularly showed anti-synchronous oscillations of the two lipids. Whereas glucose-induced PtdIns(4) P elevation required voltage-gated Ca...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (23): 4197–4208.
Published: 1 December 2007
...Gavin I. Welsh; Sophie E. Leney; Bethan Lloyd-Lewis; Matthew Wherlock; Andrew J. Lindsay; Mary W. McCaffrey; Jeremy M. Tavaré The translocation of GLUT4 to the plasma membrane underlies the ability of insulin to stimulate glucose uptake, an event that involves the activation of protein kinase B...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (22): 5335–5344.
Published: 15 November 2005
...Florent Allagnat; David Martin; Daniele F. Condorelli; Gérard Waeber; Jacques-Antoine Haefliger The gap-junction protein connexin36 (Cx36) contributes to control the functions of insulin-producing cells. In this study, we investigated whether the expression of Cx36 is regulated by glucose...
Journal Articles
J Cell Sci (2004) 117 (10): 1937–1944.
Published: 15 April 2004
... skeletal muscle. Here, we assessed whether glucose could regulate gene expression in contracting myotubes deriving from cultured muscle satellite cells. Glucose uptake increased twofold after a 30 minute treatment with a high glucose concentration, suggesting an acute glucose-stimulated glucose uptake...
Journal Articles
J Cell Sci (2002) 115 (21): 4177–4189.
Published: 1 November 2002
...Aniko Varadi; Edward K. Ainscow; Victoria J. Allan; Guy A. Rutter Recruitment of secretory vesicles to the cell surface is essential for the sustained secretion of insulin in response to glucose. At present, the molecular motors involved in this movement, and the mechanisms whereby they may...
Journal Articles
J Cell Sci (2002) 115 (11): 2433–2442.
Published: 1 June 2002
...Kay Barnes; Jean C. Ingram; Omar H. Porras; L. Felipe Barros; Emma R. Hudson; Lee G. D. Fryer; Fabienne Foufelle; David Carling; D. Grahame Hardie; Stephen A. Baldwin In the rat liver epithelial cell line Clone 9, the V max for glucose uptake is actuely increased by inhibition of oxidative...