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Keywords: Genome stability
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Journal Articles
Journal Articles
J Cell Sci (2020) 133 (1): jcs240754.
Published: 8 January 2020
... by The Company of Biologists Ltd 2020 Summary: We establish a new vector series to efficiently and stably introduce DNA sequences into the fission yeast genome, and use it to generate a set of fluorescent cell biology probes. Fission yeast Schizosaccharomyces pombe Genome stability Integrative...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (12): jcs211433.
Published: 27 June 2018
...-Universität Marburg) for help with immunofluorescence, and for Stephan Geley for providing the KIF4A-KO cell lines. Chromokinesin Fe-S cluster Genome stability Recent studies have attempted to expand the list of genes contributing to chromosome instability (CIN) in yeast. These studies...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2017) 130 (6): 1134–1146.
Published: 15 March 2017
... repeat domain requires further ATM or ATR activity. Thus, NIPBL has evolved a sophisticated response to damaged DNA that is influenced by the form of damage, suggesting a highly dynamic role for NIPBL in maintaining genomic stability. * Author for correspondence ( lena.strom@ki.se ) Competing...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2012) 125 (20): 4770–4779.
Published: 15 October 2012
... and division. Cep131 has recently been described as a basal body component essential for cilium formation, but its function in non-ciliogenic cells is unknown. We identified human Cep131 (also known as AZI1) in a screen for regulators of genome stability. We show that centrosomal localisation of Cep131 is cell...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (22): 4013–4025.
Published: 15 November 2009
... Shelterin ALT Aging Recombination Genome stability Telomeres consist of a repetitive non-coding sequence that terminates in a single-stranded overhang at the end of linear chromosomes in eukaryotes and some prokaryotes. Both the overhang and the upstream double-stranded region serve as binding...
Journal Articles
In collection:
Metabolism
J Cell Sci (2009) 122 (12): 1990–2002.
Published: 15 June 2009
... equally to this work 24 2 2009 © The Company of Biologists Limited 2009 2009 NAD + metabolism PARP DNA repair Mitosis Genome stability Poly(ADP-ribosyl)ation is a NAD + -dependent post-translational modification of proteins mediated by poly(ADP-ribose) polymerases (PARPs...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2009) 122 (8): 1258–1267.
Published: 15 April 2009
... in the maintenance of genome stability in all organisms that have been examined. Although genetic alterations in the RECQL4 gene are reported to be associated with three autosomal recessive disorders (Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes), the molecular role of RECQL4 still remains poorly...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (23): 3933–3940.
Published: 1 December 2008
..., Hospital Universitario de Canarias, Ofra s/n, La Cuesta, 38320, Tenerife, Spain 2 9 2008 © The Company of Biologists Limited 2008 2008 ATR DNA-damage signalling Cell cycle checkpoints Genome stability Rad9 Proteins involved in signalling DNA damage are critical...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2005) 118 (18): 4207–4217.
Published: 15 September 2005
... DNA replication Double parked Cdt1 Geminin Genome stability In dividing cells, the entire genome must be copied but each region of the genome must be replicated only once. Either under- or over-replication compromises genome integrity and can result in cell death or cancer. Therefore...
Journal Articles