... - 477.e5 . 10.1016/j.devcel.2017.02.003 Bateman , J. , Reddy , R. S. , Saito , H. and Van Vactor , D. ( 2001 ). The receptor tyrosine phosphatase Dlar and integrins organize actin filaments in the Drosophila follicular epithelium . Curr. Biol. 11 , 1317 - 1327...

.../ Highlighted Article: Phosphorylation and dephosphorylation regulate clustering of PAR3, a cell polarity-regulating factor, and this clustering affects the localization of PAR3 and cell–cell junctions. PAR3 PAR-3 ASPP2 aPKC Epithelium Polarity Cell polarity, one of the basic properties...

... http://www.biologists.com/user-licence-1-1/ Highlighted Article: Crosstalk between cell adhesion dynamics and actomyosin regulates epithelial cell shape. The p120-catenin protein facilitates this crosstalk through modulation of Arf1 and RhoA signalling. Cell shape Epithelium Adhesion...

... cells. Its depletion leads to apoptosis and DNA damage through separate mechanisms. Drosophila Cell polarity DNA damage PI3K Epithelium Neuroblast The polar localization of TnI prompted an analysis of well-characterized polarity proteins under TnI-deficient conditions...

...Zhimin Wang; Floris Bosveld; Yohanns Bellaïche ABSTRACT In epithelial tissue, new cell-cell junctions are formed upon cytokinesis. To understand junction formation during cytokinesis, we explored de novo formation of tricellular septate junctions (TCJs) in Drosophila epithelium. We found that upon...

.... Epithelium Lumen EFA6 ACTN1 Contractility During organogenesis, the coordinated establishment of the apico-basal polarity with the de novo formation of an apical luminal space is fundamental to the emergence of the different types of epithelia. In adult organisms, the aptitude of the internal...

... unexplored. Here, we examine the role of tight junctions during cytokinesis in the epithelium of the Xenopus laevis embryo. Depletion of the tight junction-associated proteins ZO-1 and GEF-H1 leads to altered cytokinesis duration and contractile ring geometry. Using a tension biosensor, we show...

...: Centrosomes are tightly coupled to the bipolar spindle. In Drosophila , Dynein and Mud initiate the centrosome–spindle coupling during prophase, whereas Asp is necessary to maintain it during metaphase. Drosophila Epithelium Centrosome inheritance Division Spindle During mitosis, cells...

...John D. Aplin; Peter T. Ruane; Andrew Ewald ABSTRACT At implantation, with the acquisition of a receptive phenotype in the uterine epithelium, an initial tenuous attachment of embryonic trophectoderm initiates reorganisation of epithelial polarity to enable stable embryo attachment...

... not. The rescue of FXYD5-impaired TEER by β 1 overexpression is in agreement with previous results showing that overexpression of the Na,K-ATPase β 1 subunit in the alveolar epithelium improves lung liquid clearance in rats ( Factor et al., 1998 ). Given that the effects of FXYD5 depend on the presence of Y199...

...Mathieu Mateo; Alex Generous; Patrick L. Sinn; Roberto Cattaneo ABSTRACT The epithelium is a highly organized type of animal tissue. Except for blood and lymph vessels, epithelial cells cover the body, line its cavities in single or stratified layers and support exchange between compartments...

...?’ by Siu Ngok et al. ( J. Cell Sci. 127 , 3205–3215 ). * Author for correspondence ( cstreuli@manchester.ac.uk ) Competing interests The authors declare no competing interests. © 2014. Published by The Company of Biologists Ltd 2014 Epithelium Mammary Breast Basement membrane...

...@kumc.edu ) 7 7 2011 © 2011. 2011 Extracellular matrix ECM Hydra Epithelium Morphogenesis Epithelial migration Tissue remodeling Tissues of multicellular animals are composed of cells mounted on scaffolds of extracellular matrix (ECM). The first ECM is laid down early...

... of corneal epithelium. Nature 229 , 560 -561. de Oliveira, L. R., Ribeiro-Silva, A. and Zucoloto, S. ( 2007 ). Prognostic impact of p53 and p63 immunoexpression in oral squamous cell carcinoma. J. Oral Pathol. Med. 36 , 191 -197. Di Iorio, E., Barbaro, V., Ruzza, A., Ponzin, D., Pellegrini...

... α3β1 integrin Lamellipodia Cell migration Epithelium Re-epithelialization is an essential event during the wound healing process. Impaired or delayed re-epithelialization and associated persistent epithelial defects and ulceration, represent a serious medical problem in many organs...

...Hans Schotman; Leena Karhinen; Catherine Rabouille During the epithelium remodelling such as the flattening of the Drosophila follicular epithelium, the α-integrin subunits are unconventionally secreted through a dGRASP-dependent route that is built de novo. The biogenetic process starts...

... and colonic epithelial barrier integrity. * Author for correspondence (e-mail: stappenb@pathology.wustl.edu ) 9 10 2008 © The Company of Biologists Limited 2009 2009 Microtubules Cell size Epithelium Vav proteins The mouse cecum and colon are adjacent structures with very...

... for correspondence (e-mail: velia@scripps.edu ) 5 10 2007 © The Company of Biologists Limited 2007 2007 Cytoskeleton Epithelium Tropomodulin Actin Tropomyosin Spectrin Tropomodulins (Tmods) are a conserved family of actin filament pointed-end capping proteins. Previous studies have...

.... References Ashburner, M. ( 1989 ). Drosophila: A Laboratory Handbook. New York: Cold Spring Harbor Press. Bement, W. M. and Mooseker, M. S. ( 1996 ). The cytoskeleton of the intestinal epithelium. In The Cytoskeleton (ed. J. E. Hesketh and I. F. Pryme) Vol. 3 . pp. 359 -404. Greenwich: JAI...

... ) 6 7 2004 © The Company of Biologists Limited 2004 2004 Cingulin Tight junction Epithelium Differentiation Embryoid body ES cell In vertebrate epithelial cells, tight junctions (TJs) form a circumferential apical belt that acts as a barrier that controls paracellular...