... BioCenter, 1030 Vienna, Austria. 7 3 2023 6 11 2023 © 2023. Published by The Company of Biologists Ltd 2023 http://www.biologists.com/user-licence-1-1/ Collective cell migration Epithelial morphogenesis Cell adhesion Cytoskeletal polarity Drosophila embryo Quantitative...

.... These results highlight the importance of the concerted action of extracellular syntaxin4 extruded in response to the lactogenic hormone and BM components in epithelial morphogenesis. * Author for correspondence ( y-hirai@kwansei.ac.jp ) Handling Editor: Andrew Ewald Competing interests...

...Tiffany Yu; Miho Matsuda ABSTRACT Erythrocyte protein band 4.1 like 5 (EPB41L5) is an adaptor protein beneath the plasma membrane that functions to control epithelial morphogenesis. Here we report a previously uncharacterized role of EPB41L5 in controlling ciliary function. We found that EPB41L5...

...Ricardo Cruz-Acuña; Adriana Mulero-Russe; Amy Y. Clark; Roy Zent; Andrés J. García ABSTRACT Synthetic hydrogels with controlled physicochemical matrix properties serve as powerful in vitro tools to dissect cell–extracellular matrix (ECM) interactions that regulate epithelial morphogenesis in 3D...

...: A distinctive morphological process of cell alignment in the Drosophila embryonic epithelium reveals that multiple feedback mechanisms in the Rho pathway can fine-tune tissue morphology during development. Rho signaling Epithelial morphogenesis Actomyosin contractility Developmental mechanics Non...

... Bioengineering Cylindrical confinement Epithelial morphogenesis Summary: Epithelia growing under tubular confinement are shown to detach and constrict to form a narrow tube in a process that depends on curvature of the substrate, cell shape and contractility. © 2019. Published by The Company...

... neighbours. E-cadherin trafficking Epithelial morphogenesis Cell adhesion Cell–cell adhesion physically links cells within stable cell sheets, while also contributing to dynamic morphogenetic events such as directional proliferation, cell sorting and cell shape regulation ( Stepniak et al...

... and junctional complexes re-formed. We observed similar epithelial organization during mammary morphogenesis in organotypic culture and in vivo. We conclude that mammary epithelial morphogenesis involves a reversible, spatially limited, reduction in polarity and intercellular junctions and active individualistic...

... affects the cytoskeletal network, resulting in changes in cell shape and eventually differentiation, which in turn reflect the activity of this protein during epithelial morphogenesis and development. In fully polarized Caco2 cells, a dense microtubular network runs parallel to the apical membrane...

... ratio. Together, our results elucidate a mechanism that mediates Crb function and further define the role of PI3K and Rac1 in epithelial morphogenesis, allowing for a better understanding of how distinct membrane domains are regulated in polarized epithelial cells. * Author for correspondence...

... © The Company of Biologists Limited 2009 2009 Integrin Epithelial morphogenesis Adhesion GATA4 MAP kinase Integrins are extracellular matrix (ECM) receptors composed of two noncovalently linked subunits, α and β. They have been implicated in the regulation of many cellular...

... epithelial motility, cell-cell adhesion via cadherins controls the remodelling of epithelial sheets. We have used the Drosophila wing epithelium to demonstrate that cell-ECM interactions mediated by integrins also regulate the changes in cell shape that underly epithelial morphogenesis. We show...

... and circadiam rhythms. Genetics 128 , 571 -582. Oda, H. and Tsukida, S. ( 1999 ). Dynamic features of adherens junctions during Drosophila embryonic epithelial morphogenesis revealed by a D α-catenin-GFP fusion protein. Dev. Genes Evol. 209 , 218 -225. Rankin, T. L., O'Brien, M., Lee, E...

...-Met Epithelial morphogenesis Hepatic development and differentiation HNF1α HNF4 Snail Liver development in the vertebrate embryo is a multistep process. The primary hepatic bud appears at 8.5 to 9 days of development in the mouse as a thickening of the ventral foregut endoderm, near...