... acid sphingomyelinase. Increased expression of cathepsin D in the skin has been reported in wound healing, psoriasis and skin tumors. We explored specific functions of cathepsin D during epidermal differentiation. Protein expression and enzymatic activity of cathepsin D increased in differentiated...

... junctions Deafness Skin disorder Epidermal differentiation In solid tissues of metazoans, most cells form gap junctions: clusters of gated intercellular channels that directly connect the cytoplasm of neighboring cells and thereby allow the passage of small ions, metabolites and other signaling...