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Keywords: Diacylglycerol
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Journal Articles
J Cell Sci (2023) 136 (3): jcs260568.
Published: 2 February 2023
.... Phosphatidic acid (PA) and diacylglycerol (DG) can both serve as biosynthetic precursors for membrane lipid synthesis. How they are regulated in time and space and what the implications are of changes in their flux for mitotic fidelity are largely unknown. Using genetically encoded PA and DG probes, we show...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (11): jcs213876.
Published: 11 June 2018
... homeostasis. ESCRT-, V-ATPase- and vacuole protein sorting-mutants negatively affect LD consumption, independent of lipophagy. Loss of ESCRT function leads to the accumulation of LD-derived diacylglycerol (DAG), preventing its conversion into phosphatidic acid (PA) and membrane lipids. In addition, channeling...
Includes: Supplementary data
Journal Articles
In collection:
Lipid Biology
J Cell Sci (2013) 126 (12): 2641–2655.
Published: 15 June 2013
...Enric Gutiérrez-Martínez; Inés Fernández-Ulibarri; Francisco Lázaro-Diéguez; Ludger Johannes; Susan Pyne; Elisabet Sarri; Gustavo Egea Summary The inhibition of phosphatidic acid phosphatase (PAP) activity by propanolol indicates that diacylglycerol (DAG) is required for the formation of transport...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (6): 927–938.
Published: 15 March 2010
...Takuro Numaga; Motohiro Nishida; Shigeki Kiyonaka; Kenta Kato; Masahiro Katano; Emiko Mori; Tomohiro Kurosaki; Ryuji Inoue; Masaki Hikida; James W. Putney, Jr; Yasuo Mori Ca 2+ signaling mediated by phospholipase C that produces inositol 1,4,5-trisphosphate [Ins(1,4,5) P 3 ] and diacylglycerol (DAG...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (12): 1963–1969.
Published: 15 June 2009
... in lamina disassembly and NEBD independently of centrosomes, NPCs and gp210. * Author for correspondence (e-mail: mattaj@embl.de ) 9 3 2009 © The Company of Biologists Limited 2009 2009 Nuclear-envelope breakdown Lipin Lamin Diacylglycerol The endoplasmic reticulum...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2006) 119 (10): 2084–2094.
Published: 15 May 2006
...+ release from internal stores, the majority of the requirement for PtdIns(4,5) P 2 hydrolysis occurs downstream of Ca 2+ signalling - as shown in permeabilised cells, where the inositol (1,4,5)-trisphosphate-Ca 2+ pathway is bypassed. Neither generation of the PtdIns(4,5) P 2 metabolite, diacylglycerol...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
In collection:
Lipid Biology
J Cell Sci (1991) 100 (1): 145–152.
Published: 1 September 1991
... may produce at least some of its biological effects in macrophages by conversion to AAG. * Author for correspondence 04 03 1991 23 05 1991 © 1991 by Company of Biologists 1991 diacylglycerol protein kinase C ether lipids Platelet-activating factor (1-O-alkyl-2...
Journal Articles
J Cell Sci (1991) 98 (2): 159–168.
Published: 1 February 1991
...Paul M. Larsen; Tung-Ling L. Chen; Stephen M. Wolniak ABSTRACT Neomycin has been reported to inhibit polyphosphoinositide cycling by preventing the hydrolysis of phosphatidylinositol 4,5-bisphosphate into inositol 1,4,5-trisphosphate and 1,2-diacylglycerol. Inositol 1,4,5-trisphosphate, through...