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Keywords: Cytoskeleton
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Journal Articles
In collection:
Mechanobiology
J Cell Sci (2022) 135 (22): jcs259769.
Published: 18 November 2022
... the sophisticated force-generation machinery of the cell, the cytoskeleton. All regions of the cell are connected via mechanical linkages, enabling the whole cell to function as a mechanical system. In this Review, we define some of the key concepts of how this machinery functions, highlighting the critical...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (11): jcs259893.
Published: 9 June 2022
... Cytoskeleton Centre National de la Recherche Scientifique http://dx.doi.org/10.13039/501100004794 Université de Bordeaux http://dx.doi.org/10.13039/501100006251 Agence Nationale de la Recherche http://dx.doi.org/10.13039/501100001665 ANR-20-CE91-0003 LabEx...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (8): jcs259493.
Published: 3 May 2022
... of nuclear stiffness. Cancer Metastasis Cell migration Cytoskeleton Nucleus Nuclear envelope Emerin Src Mechanotransduction Melanoma Research Alliance http://dx.doi.org/10.13039/100005190 688232 American Cancer Society http://dx.doi.org/10.13039/100000048 RSG-20-019...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton , Imaging
J Cell Sci (2022) 135 (7): jcs259234.
Published: 8 April 2022
..., frequently contained lumenal particles and exhibited lattice defects. Investigation of the effect of absence of doublecortin, a neurodevelopmental cytoskeleton regulator, on growth cone cytoskeleton showed no major anomalies in overall growth cone organisation or in F-actin subpopulations. However, our data...
Includes: Supplementary data
Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2022) 135 (4): jcs258960.
Published: 17 February 2022
..., localized proximally at the junction with striated rootlets. Knocking down either gene caused defects in BB docking, spacing and polarization. Moreover, their depletion impaired the apical cytoskeleton and altered ciliary beating. Consequently, cilia-powered fluid flow was greatly reduced in morphant...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2022) 135 (1): jcs258850.
Published: 10 January 2022
... targeting septin octamers to microtubules. Modulation of this targeting affects microtubule stability and actomyosin fiber distribution and tension in cells. Actin Cytoskeleton Microtubule Septin SEPT9 Agence Nationale de la Recherche http://dx.doi.org/10.13039/501100001665 ANR-17...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (16): jcs258465.
Published: 24 August 2021
... Biol. 12 , 761 - 770 . 10.1080/15476286.2015.1051302 Summary: Developmentally regulated expression of the miRISC protein GW182 plays an important role in determining dendritic arborization by regulating somatodendritic translation and actin cytoskeletal dynamics. Cytoskeleton...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and Flagella
J Cell Sci (2021) 134 (16): jcs258544.
Published: 18 August 2021
... function. Centrosome Cilia Cytoskeleton Mechanobiology Organelle assembly Rootlets Medical Research Council http://dx.doi.org/10.13039/501100007155 University of Cambridge http://dx.doi.org/10.13039/501100000735 Isaac Newton Trust http://dx.doi.org/10.13039...
Journal Articles
J Cell Sci (2021) 134 (15): jcs258484.
Published: 5 August 2021
... assays to dissect the complex interactions of septins with cell membranes and the actin and microtubule cytoskeleton. * Present address: Institut Curie, Université PSL, Sorbonne Université, CNRS UMR 168, Laboratoire Physico Chimie Curie, 75005 Paris, France. ‡ Authors for correspondence...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (14): jcs245464.
Published: 23 July 2021
...Akanksha Thawani; Sabine Petry ABSTRACT As one of four filament types, microtubules are a core component of the cytoskeleton and are essential for cell function. Yet how microtubules are nucleated from their building blocks, the αβ-tubulin heterodimer, has remained a fundamental open question since...
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2021) 134 (6): jcs240226.
Published: 22 March 2021
... surface, thereby reorganizing their entire cytoskeleton ( Iendaltseva et al., 2020 ). Fibronectin distribution in vivo follows a similar dot pattern, being located at adhesion plaques in the BM between pericytes and ECs. This study highlights how common microfabrication techniques and state-of-the-art...
Journal Articles
J Cell Sci (2021) 134 (6): jcs247866.
Published: 11 March 2021
... Ltd 2021 Summary: Clarification of the relationship between two tension-regulated proteins, LIMD1 and TRIP6, and identification of a role for TRIP6 in regulating the organization of the actin cytoskeleton. Mechanotransduction Tension Hippo Junction LIMD1 Cytoskeleton...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (6): jcs256180.
Published: 11 March 2021
... segment Ranbp2 are shown to be based on NF186-cross-reacting antibodies and the intrinsic ability of an N-terminal fragment of Ranbp2 to bind to stable microtubules. Axon Cytoskeleton Antibody Ranbp2 Nup358 The axon initial segment (AIS) is essential for the proper generation of axonal...
Journal Articles
J Cell Sci (2021) 134 (5): jcs252403.
Published: 8 March 2021
... the reorganization of the cytoskeleton and positioning of intracellular organelles. We show this model is amenable to screening C. trachomatis mutants for defects in the fusion of pathogenic vacuoles, the recruitment of intracellular organelles and inhibition of cell death. Moreover, we reconstructed a primary...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (5): jcs251298.
Published: 25 February 2021
... manner, and that this is necessary for their contraction and remodeling into rings. We demonstrate that the structural integrity of these incipient septin discs requires both an intact F-actin and microtubule cytoskeleton and provide fundamental new insight into their functional organization within...
Includes: Supplementary data
Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2021) 134 (4): jcs257006.
Published: 22 February 2021
... is critical for generating functional multi-ciliated epithelium in the mouse oviduct. Basal body Cytoskeleton Oviduct Planar cell polarity Reproduction Super-resolution microscopy Japan Society for the Promotion of Science http://dx.doi.org/10.13039/501100001691 25291054 15H01220...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (3): jcs248393.
Published: 10 February 2021
... contexts, including their prominent roles in developing nervous systems. These diverse roles are achieved through Trio protein interactions with membrane receptors, cytoskeleton-interacting proteins, lipids, endocytic machinery, kinases and Rho family GTPases in the cell ( Fig. 1 ). Recent studies have...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (3): jcs248385.
Published: 8 February 2021
...Gillian DeWane; Alicia M. Salvi; Kris A. DeMali ABSTRACT Attention has long focused on the actin cytoskeleton as a unit capable of organizing into ensembles that control cell shape, polarity, migration and the establishment of intercellular contacts that support tissue architecture. However...
Journal Articles
J Cell Sci (2020) 133 (20): jcs244731.
Published: 30 October 2020
..., we discuss the mechanisms of megakaryocyte differentiation and how bona fide platelets are brought into circulation. Megakaryocyte Platelet Cytoskeleton Mechanobiology Blood platelets are crucial during hemostasis to prevent hemorrhages. At sites of vascular injury, circulating...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (18): jcs248047.
Published: 15 September 2020
...Jana Jentzsch; Adal Sabri; Konstantin Speckner; Gertrud Lallinger-Kube; Matthias Weiss; Klaus Ersfeld ABSTRACT The shape of kinetoplastids, such as Trypanosoma brucei , is precisely defined during the stages of the life cycle and governed by a stable subpellicular microtubule cytoskeleton. During...
Includes: Supplementary data