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Keywords: Cell mechanics
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Journal Articles
J Cell Sci (2022) 135 (21): jcs259208.
Published: 3 November 2022
... surface forces to regulate growth and morphogenesis. Cell wall Growth Cell mechanics Morphogenesis Plants Fungi Yeast Centre National de la Recherche Scientifique http://dx.doi.org/10.13039/501100004794 Université Paris Cité Ecole Polytechnique...
Journal Articles
J Cell Sci (2022) 135 (16): jcs259356.
Published: 16 August 2022
.... This Review discusses the mechanical properties of spectrins, their organization in red blood cells and neurons, and the contribution to the mechanical properties of these cells. Red blood cell elasticity Axonal cytoskeleton Cell mechanics Membrane-associated periodic skeleton Spectrin scaffold...
Journal Articles
J Cell Sci (2022) 135 (15): jcs259355.
Published: 9 August 2022
... et al., 2005 ; Efremov et al., 2019 ; Latorre et al., 2018 ; Turlier et al., 2016 ), for which no unified theory exists ( Dumont and Prakash, 2014 ). Consequently, we need to broaden our views of cell mechanics away from continuum mechanics and advocate that mechanical properties need...
Journal Articles
J Cell Sci (2022) 135 (12): jcs259379.
Published: 21 June 2022
... and cytomechanical properties in adult stem cell differentiation have been widely appreciated, how they contribute to mechanotransduction in PSCs is less well understood. Here, we discuss recent insights into the interplay of cellular architecture, cell mechanics and the pluripotent states of PSCs. Notably...
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2021) 134 (6): jcs240226.
Published: 22 March 2021
... ECs, is embedded in the vascular BM and has a protruding cell body. Pericyte Cytoskeleton Contractility Cell migration Cell mechanics In vitro models Summary: This Review focuses on forces generated by pericytes, solid and fluid mechanical forces exerted on pericytes...
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2020) 133 (13): jcs243873.
Published: 8 July 2020
... stress fibers needed to break tensional symmetry. Cofilin Stress fiber Tension Front-back polarity Cell mechanics Cell migration is critical to many developmental and pathological processes, including wound healing, embryogenesis and cancer progression ( Friedl and Gilmour, 2009 ). Many...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (12): jcs216010.
Published: 21 June 2018
... to characterize mechanical aspects of cell monolayers. Mechanobiology Cell mechanics Cell rheology Cell structure Substrate stiffness * Author for correspondence ( krisdahl@cmu.edu ) Competing interests The authors declare no competing or financial interests. 25 1 2018 4 5...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (11): 1965–1978.
Published: 1 June 2017
... cells. This specific form of mechanical signaling downregulates integrin β3 resulting in increased cofilin activity. Invadopodia Cell mechanics Cell invasion Cancer Cofilin Invasion is an acquired cellular process that drives the progression of cancer into the metastatic cascade...
Includes: Supplementary data
Journal Articles
In collection:
Cell Migration
J Cell Sci (2017) 130 (4): 689–696.
Published: 15 February 2017
... and phosphorylation regulate myosin turnover. Cytoskeletal dynamics Cell mechanics Embryonic wound healing Drosophila Fluorescence recovery after photobleaching Laser ablation Coordinated cell movements drive embryonic development and tissue repair, and are implicated in cancer metastasis...
Includes: Supplementary data
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2016) 129 (7): 1293–1304.
Published: 1 April 2016
... their structure, force-dependent assembly and force generation capacity. Cell mechanics Focal adhesions Mechanosensitivity Sarcomeres Stress fibers The above scenario we propose suggests the dynamic regulation of stress fiber length and tension by a dual mechanism involving, on one hand, actin...
Journal Articles
J Cell Sci (2014) 127 (14): 3005–3015.
Published: 15 July 2014
.... Published by The Company of Biologists Ltd 2014 Cell mechanics Mechanotransduction Extra-cellular matrix Nucleus Nucleoskeleton Proteostasis Evolution has likely driven our tissues and organs to fulfill their roles with optimal efficiency and, of course, viability. Mature tissues need...
Journal Articles
J Cell Sci (2013) 126 (14): 3021–3030.
Published: 15 July 2013
.... Published by The Company of Biologists Ltd 2013 Cell mechanics Mechanotransduction Stress fibers Focal adhesions Laser ablation Fluorescence resonance energy transfer Over the past decade, it has become clear that the application of tensile force by cells on their surroundings plays key...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (3): 603–613.
Published: 1 February 2012
... ( a@pellinglab.net ) 20 9 2011 © 2012. 2012 Actin Atomic force microscopy Cell mechanics Cytoskeleton Mechanotransduction Strain Mechanotransduction, the transmission of a mechanical stimulus into a useful chemical or biochemical signal, is a concept being rigorously studied...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (1): 9–18.
Published: 1 January 2011
... ) that are specific to their cell type and functions, and that are determined by their intrinsic mechanical properties and interactions with their mechanical environment. Abnormalities in cell mechanical properties or mechanical environment can result in altered cell function and disease, including malignancy, loss...
Journal Articles
J Cell Sci (2010) 123 (3): 297–308.
Published: 1 February 2010
... to a cell using a bead or a glass rod to contact the cell ( Choquet et al., 1997 ; Riveline et al., 2001 ; Wang et al., 1993 ). * Author for correspondence ( discher@seas.upenn.edu ) © 2010. 2010 Cell mechanics Matrix Nucleus Mesenchyme in embryos consists of loosely packed cells...
Journal Articles
J Cell Sci (2009) 122 (18): 3233–3241.
Published: 15 September 2009
... ). A bottom-up approach to cell mechanics. Nat. Phys. 2 , 231 -238. Bausch, A. R., Moller, W. and Sackmann, E. ( 1999 ). Measurement of local viscoelasticity and forces in living cells by magnetic tweezers. Biophys. J. 76 , 573 -579. Biot, M. ( 1941 ). General theory of three-dimensional...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2006) 119 (9): 1760–1768.
Published: 1 May 2006
...@jhu.edu ; jslee@jhu.edu ) 19 1 2006 © The Company of Biologists Limited 2006 2006 Cell mechanics Rho GTPases Fluid shear stress Actin Microtubule Fluid flows are necessary for proper cellular proliferation and growth, as well as the regulation of various physiological...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (9): 1903–1913.
Published: 1 May 2006
...), and that the flattening force can plausibly be generated by the known concentrations of unconventional myosins at the leading edge. * Author for correspondence (e-mail: herantm@bu.edu ) 5 1 2006 © The Company of Biologists Limited 2006 2006 Membrane tension Lamella Cell mechanics Cell...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2005) 118 (9): 1789–1797.
Published: 1 May 2005
... 1 2005 © The Company of Biologists Limited 2005 2005 Phagocytosis Neutrophil Membrane Tension Cell mechanics Phagocytosis is a key capability through which the neutrophil fulfills its role as foot-soldier of the immune system. Although considerable effort has been devoted...
Journal Articles
J Cell Sci (2003) 116 (8): 1481–1491.
Published: 15 April 2003
...-matrix adhesions. J. Cell Sci. 114 , 3583 -3590. * Author for correspondence (e-mail: matthew.petroll@utsouthwestern.edu ) 7 1 2003 © The Company of Biologists Limited 2003 2003 Focal adhesions Focal complexes Cell motility Collagen lattice Actomyosin Cell mechanics...
Includes: Multimedia, Supplementary data