... of cortical organelles during cell division in the ciliate Tetrahymena thermophila . Cell cortex Ciliate Patterning Polarity National Institutes of Health http://dx.doi.org/100000002 R01GM135444 R01GM110413 Ministry of Education, Culture, Sports, Science and Technology http...

... a dataset of candidate cortex mechanics regulators. Actin Cell cortex Cell division Cortical tension Mass spectrometry Septin Medical Research Council http://dx.doi.org/10.13039/501100000265 MC_UU_12018/5 European Research Council http://dx.doi.org/10.13039/100010663...

... as barriers and scaffolds on the cell cortex. However, little is known about the mechanism that governs the recruitment and localization of the septin complex to the cell cortex. Here, we identified the Cdc42 GTPase-activating protein Rga6 as a key protein involved in promoting the localization of the septin...

... with assembly through liquid–liquid phase separation. Insulin secretion Cell cortex Focal adhesion Liquid–liquid phase separation Knock-in mouse Single-molecule imaging ZonMw http://dx.doi.org/10.13039/501100001826 91207010 91216006 Nederlandse Organisatie voor...

... of actin filaments are enriched at cortical regions rich in Rho signaling in syncytial Drosophila embryos depending on the actin regulator Dia and Rho kinase. Cell cortex Epithelial domain Subapical Formin Dia Actin Capping protein Myosin Drosophila Embryo Chinese Scholarship...

..., the asymmetry index (ASI) of cortical LifeAct was calculated by first obtaining mean fluorescence values from selected regions of the cell cortex in the anterior and posterior halves of the zygote in background subtracted images. We then calculated ASI according to the equation ASI=(A−P)/[2(A+P)], where A and P...

... interactions between actin and myosin-2 at the single-filament level translate into contraction at the network scale by performing time-lapse imaging on reconstituted quasi-2D networks mimicking the cell cortex. We observe myosin end-dwelling after it runs processively along actin filaments. This leads...

... and Sun, 2015 ; Tao et al., 2017 ): (1) where σ a is the active contractile stress in the cell cortex, h is the cortical thickness, T is the membrane tension, Δ P is the hydrostatic pressure difference across the membrane, H is the cell surface mean curvature, and A is the area over which...

... species induce dephosphorylation of pTyr23AnxA2 located in the PML bodies of the nucleus, whereas AnxA2 associated with F-actin at the cell cortex is Tyr23 phosphorylated. The H 2 O 2 -induced responses in both compartments are transient and the pTyr23AnxA2 accumulating at the cell cortex is subsequently...

...Andrea I. McClatchey ABSTRACT The cell cortex is a dynamic and heterogeneous structure that governs cell identity and behavior. The ERM proteins (ezrin, radixin and moesin) are major architects of the cell cortex, and they link plasma membrane phospholipids and proteins to the underlying cortical...

... and exocytosed upon stimulation. Previously, we have reported that newly formed secretory granules of PC12 cells are transported in a microtubule-dependent manner from the trans-Golgi network to the F-actin-rich cell cortex, where they undergo short directed movements and exhibit a homogeneous distribution. Here...

... tubulin. We monitored these components of the cytoskeleton as the cells prepared for division at preprophase and progressed through mitosis to cytokinesis. Reorganisation of the interphase cortical cytoskeleton results in preprophase bands of both F-actin and microtubules that coexist in the cell cortex...

... it is longitudinally. Analysis of the orientation of circumferential filaments shows that it is composed of discrete domains of up to 10 μ m 2 . Relative movements between domains could allow substantial changes of cell shape without disrupting the unit structure of the lattice, thus allowing the cell cortex to retain...