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Keywords: Caenorhabditis elegans
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Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2021) 134 (17): jcs258428.
Published: 6 September 2021
.... Downregulation of lmn-1 , the single Caenorhabditis elegans lamin gene, increased animal size and fat content specifically in DR animals. The LMN - 1 protein acts in the mTOR pathway, upstream of RAPTOR and S6 kinase β1 (S6K), a key component of and target of the mechanistic target of rapamycin (mTOR) complex 1...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2019) 132 (12): jcs228023.
Published: 17 June 2019
... and functional interdependence of actin and dynamin during this process remain inadequately understood. Here, based on small-scale screening and in vivo live-imaging techniques, we identified a novel set of molecules underlying CCP scission in the multicellular organism Caenorhabditis elegans . We found...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2017) 130 (12): 2007–2017.
Published: 15 June 2017
... phosphoinositide 3-kinase (PI3K), to generate PI(3)P and recruit PI(3)P-binding proteins. Loss of Rab5 and loss of Vps34 have opposite effects on endosome size, suggesting that our understanding of how Rab5 and PI(3)P cooperate is incomplete. Here, we report a novel regulatory loop whereby Caenorhabditis elegans...
Includes: Supplementary data
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In collection:
Membrane Trafficking
J Cell Sci (2016) 129 (7): 1490–1499.
Published: 1 April 2016
... complex comprising VPS-22/EAP30, VPS-36/EAP45 and two VPS-25/EAP20 subunits, has also been associated with regulation of gene expression ( Irion and St Johnston, 2007 ; Kamura et al., 2001 ; Jin et al., 2005 ). Studies of the ESCRT functions during Caenorhabditiselegans development indicate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (2): 341–353.
Published: 15 January 2016
...Hyemin Min; Yhong-Hee Shim; Ichiro Kawasaki ABSTRACT In Caenorhabditis elegans , the mechanisms regulating germline apoptosis remain largely unknown, except for the core machinery. Here, we found that mutants of pgl-1 and pgl-3 , encoding members of a family of constitutive protein components...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (6): 1090–1096.
Published: 15 March 2015
... or financial interests. 6 10 2014 27 01 2015 © 2015. Published by The Company of Biologists Ltd 2015 Caenorhabditis elegans LEMD2 LINC Emerin Laminopathy Nuclear envelope The nuclear envelope is an essential structure in eukaryotic cells. It separates nuclear...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (18): 4136–4146.
Published: 15 September 2013
.... , Niwa   M. ( 2007 ). A novel role in cytokinesis reveals a housekeeping function for the unfolded protein response.   J. Cell Biol.   177 , 1017 – 1027 . 10.1083/jcb.200702101 Brenner   S. ( 1974 ). The genetics of Caenorhabditis elegans.   Genetics   77 , 71 – 94 . Calfon   M...
Includes: Supplementary data
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J Cell Sci (2013) 126 (9): 2079–2091.
Published: 1 May 2013
...Yee Lian Chew; Xiaochen Fan; Jürgen Götz; Hannah R. Nicholas Summary Protein with tau-like repeats (PTL-1) is the sole Caenorhabditis elegans homolog of tau and MAP2, which are members of the mammalian family of microtubule-associated proteins (MAPs). In mammalian neurons, tau and MAP2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (7): 1692–1702.
Published: 1 April 2013
...Emily Chan; Jeremy Nance Summary Polarization of early embryos provides a foundation to execute essential patterning and morphogenetic events. In Caenorhabditis elegans , cell contacts polarize early embryos along their radial axis by excluding the cortical polarity protein PAR-6 from sites of cell...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (3): 850–859.
Published: 1 February 2013
... for correspondence ( peter.boag@monash.edu ) 21 11 2012 © 2013. Published by The Company of Biologists Ltd 2013 eIF4E transporter P granule Germ granules Translational regulation Caenorhabditis elegans Germ cells are unique as they are immortal and pluripotent. In all species...
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Journal Articles
Journal Articles
J Cell Sci (2010) 123 (16): 2717–2724.
Published: 15 August 2010
... mechanisms. References Ahringer J. , Kimble J. ( 1991 ). Control of the sperm-oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3′ untranslated region . Nature 349 , 346 - 348 . Ariz M. , Mainpal R. , Subramaniam K. ( 2009 ). C. elegans RNA...
Includes: Supplementary data
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J Cell Sci (2006) 119 (23): 4811–4818.
Published: 1 December 2006
...Erin J. Cram; Hongyu Shang; Jean E. Schwarzbauer Cell migration is essential during embryonic development and tissue morphogenesis. During gonadogenesis in the nematode Caenorhabditis elegans , migration of the distal tip cells forms two U-shaped gonad arms . Malformation results if the distal tip...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (15): 3327–3338.
Published: 1 August 2005
... a regulatory domain of the kinase occupies the catalytic site and calcium/calmodulin activates the kinase by binding to and displacing this regulatory domain. A single putative ortholog of CaMKII, encoded by unc-43 , is present in the Caenorhabditis elegans nervous system. Here we examined UNC-43 subcellular...
Journal Articles