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.... T. , Rothberg , K. G. , Azizoglu , D. B. , Volk , E. , Liao , J.-C. and Liou , J. ( 2013 ). Feedback regulation of receptor-induced Ca2+ signaling mediated by E-Syt1 and Nir2 at endoplasmic reticulum-plasma membrane junctions . Cell Rep 5 , 813 - 825 . 10.1016...

View article titled, Enforced tethering elongates the cortical endoplasmic reticulum and limits store-operated Ca 2+ entry

Includes: Supplementary data

Journal Articles

CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors

Vikas Arige, Lara E. Terry, Sundeep Malik, Taylor R. Knebel, Larry E. Wagner II, David I. Yule

J Cell Sci (2021) 134 (20): jcs258875.

DOI: https://doi.org/10.1242/jcs.258875

Published: 26 October 2021

.... and Bezprozvanny , I. ( 2005 ). Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease . Proc. Natl. Acad. Sci. USA 102 , 2602 - 2607 . 10.1073/pnas.0409402102 Terry , L. E. , Alzayady , K. J. , Wahl , A. M. , Malik , S. and Yule , D. I...

View article titled, CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors

Includes: Supplementary data

Journal Articles

The p.E152K-STIM1 mutation deregulates Ca 2+ signaling contributing to chronic pancreatitis

In collection:

Cell Biology and Disease

J Cell Sci (2021) 134 (3): jcs244012.

DOI: https://doi.org/10.1242/jcs.244012

Published: 10 February 2021

... STIM1 mutation impairs store-operated calcium entry and natural killer cell effector function without clinical immunodeficiency . J. Allergy Clin. Immunol. 137 , 955 - 957.e8 . 10.1016/j.jaci.2015.08.051 Petersen , O. H. ( 2009 ). Ca2+ signaling in pancreatic acinar cells: physiology...

View article titled, The p.E152K-STIM1 mutation deregulates Ca 2+ signaling contributing to chronic pancreatitis

Includes: Supplementary data

Journal Articles

TPC2-mediated Ca 2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos

Chenxi Guo, Sarah E. Webb, Ching Man Chan, Andrew L. Miller

J Cell Sci (2020) 133 (13): jcs244780.

DOI: https://doi.org/10.1242/jcs.244780

Published: 10 July 2020

View article titled, TPC2-mediated Ca 2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos

Includes: Supplementary data

Journal Articles

Convergent Met and voltage-gated Ca 2+ channel signaling drives hypermigration of Toxoplasma -infected dendritic cells

Einar B. Ólafsson, Arne L. ten Hoeve, Xiaoze Li-Wang, Linda Westermark, Manuel Varas-Godoy, Antonio Barragan

J Cell Sci (2021) 134 (5): jcs241752.

DOI: https://doi.org/10.1242/jcs.241752

Published: 21 April 2020

View article titled, Convergent Met and voltage-gated Ca 2+ channel signaling drives hypermigration of Toxoplasma -infected dendritic cells

Includes: Supplementary data

Journal Articles

The inactivation domain of STIM1 acts through intramolecular binding to the coiled-coil domain in the resting state

Sang Kwon Lee, Min-hsun Lee, Su Ji Jeong, Xianan Qin, Ah Reum Lee, Hyokeun Park, Chan Young Park

J Cell Sci (2020) 133 (1): jcs237354.

DOI: https://doi.org/10.1242/jcs.237354

Published: 8 January 2020

View article titled, The inactivation domain of STIM1 acts through intramolecular binding to the coiled-coil domain in the resting state

Includes: Supplementary data

Journal Articles

Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells

Deekshitha Jetta, Philip A. Gottlieb, Deepika Verma, Frederick Sachs, Susan Z. Hua

J Cell Sci (2019) 132 (11): jcs226076.

DOI: https://doi.org/10.1242/jcs.226076

Published: 12 June 2019

View article titled, Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells

Includes: Supplementary data

Journal Articles

Evidence for a regulated Ca 2+ entry in proximal tubular cells and its implication in calcium stone formation

In collection:

Cell Biology and Disease

Cliff-Lawrence Ibeh, Allen J. Yiu, Yianni L. Kanaras, Edina Paal, Lutz Birnbaumer, Pedro A. Jose, Bidhan C. Bandyopadhyay

J Cell Sci (2019) 132 (9): jcs225268.

DOI: https://doi.org/10.1242/jcs.225268

Published: 30 April 2019

... epithelial cells . J. Biol. Chem. 292 , 11388 - 11399 . 10.1074/jbc.M116.752352 Bandyopadhyay , B. C. , Swaim , W. D. , Liu , X. , Redman , R. S. , Patterson , R. L. and Ambudkar , I. S. ( 2005 ). Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex...

View article titled, Evidence for a regulated Ca 2+ entry in proximal tubular cells and its implication in calcium stone formation

Includes: Supplementary data

Journal Articles

Leucine-rich repeat-containing 8B protein is associated with the endoplasmic reticulum Ca 2+ leak in HEK293 cells

Arijita Ghosh, Nitin Khandelwal, Arvind Kumar, Amal Kanti Bera

J Cell Sci (2017) 130 (22): 3818–3828.

DOI: https://doi.org/10.1242/jcs.203646

Published: 15 November 2017

View article titled, Leucine-rich repeat-containing 8B protein is associated with the endoplasmic reticulum Ca 2+ leak in HEK293 cells

Includes: Supplementary data

Journal Articles

Engineering mammalian cells to seek senescence-associated secretory phenotypes

Anam Qudrat, Janice Wong, Kevin Truong

J Cell Sci (2017) 130 (18): 3116–3123.

DOI: https://doi.org/10.1242/jcs.206979

Published: 15 September 2017

... 1 . Fig. 1. In IL6 detector cells expressing the red Ca2+ sensor RCaMP1.07 (labeling the PM) and chimeric IL6 receptor (IL6Rchi), a Ca2+ signal is triggered in response to extracellular IL6. (A) Schematic of the mechanism of activation of IL6Rchi. (B) Representative images showing IL6 detector...

View article titled, Engineering mammalian cells to seek senescence-associated secretory phenotypes

Includes: Supplementary data

Journal Articles

A novel ATP-synthase-independent mechanism coupling mitochondrial activation to exocytosis in insulin-secreting cells

In collection:

Mitochondria

Umberto De Marchi, Aurelie Hermant, Jonathan Thevenet, Yann Ratinaud, Jaime Santo-Domingo, Denis Barron, Andreas Wiederkehr

J Cell Sci (2017) 130 (11): 1929–1939.

DOI: https://doi.org/10.1242/jcs.200741

Published: 1 June 2017

...-to-absent intracellular Ca2+ responses to methylsuccinate. (A–D) Bi-parametric analysis of Ca2+ signals measured in INS-1E cells expressing the cytosolic Ca2+-probe YC3.6, and stimulated with glucose or methylsuccinate. (A,B) Examples of cytosolic Ca2+ responses in individual INS-1E cells stimulated...

View article titled, A novel ATP-synthase-independent mechanism coupling mitochondrial activation to exocytosis in insulin-secreting cells

Journal Articles

Nitric oxide mediates stretch-induced Ca 2+ oscillation in smooth muscle

Ji Zheng, Kui Zhai, Yingxiao Chen, Xu Zhang, Lin Miao, Bin Wei, Guangju Ji

J Cell Sci (2016) 129 (12): 2430–2437.

DOI: https://doi.org/10.1242/jcs.180638

Published: 15 June 2016

View article titled, Nitric oxide mediates stretch-induced Ca 2+ oscillation in smooth muscle

Includes: Supplementary data

Journal Articles

TRPP2-dependent Ca 2+ signaling in dorso-lateral mesoderm is required for kidney field establishment in Xenopus

Mélinée Futel, Catherine Leclerc, Ronan Le Bouffant, Isabelle Buisson, Isabelle Néant, Muriel Umbhauer, Marc Moreau, Jean-François Riou

J Cell Sci (2015) 128 (5): 888–899.

DOI: https://doi.org/10.1242/jcs.155499

Published: 1 March 2015

... at the early neurula stage. In contrast, lhx1, osr1 and osr2 expression is not affected. At the late neurula stage, pax8 expression is severely inhibited. In contrast, lhx1, osr1 and osr2 expression is not affected, indicating that Ca2+ signaling is acting upstream of pax8, but does not act in a general...

View article titled, TRPP2-dependent Ca 2+ signaling in dorso-lateral mesoderm is required for kidney field establishment in Xenopus

Includes: Supplementary data

Journal Articles

Bcl-2 binds to and inhibits ryanodine receptors

Tim Vervliet, Elke Decrock, Jordi Molgó, Vincenzo Sorrentino, Ludwig Missiaen, Luc Leybaert, Humbert De Smedt, Nael Nadif Kasri, Jan B. Parys, Geert Bultynck

J Cell Sci (2014) 127 (12): 2782–2792.

DOI: https://doi.org/10.1242/jcs.150011

Published: 15 June 2014

View article titled, Bcl-2 binds to and inhibits ryanodine receptors

Includes: Supplementary data

Journal Articles

Apart from its known function, the plasma membrane Ca 2+ ATPase can regulate Ca 2+ signaling by controlling phosphatidylinositol 4,5-bisphosphate levels

John T. Penniston, Rita Padányi, Katalin Pászty, Karolina Varga, Luca Hegedűs, Agnes Enyedi

J Cell Sci (2014) 127 (1): 72–84.

DOI: https://doi.org/10.1242/jcs.132548

Published: 1 January 2014

...; *** P <0.0001, Student's t -test. Fig. 4. Effect of PMCA constructs on PtdIns(4,5)P2 and Ca2+ signaling during receptor-mediated PLC activation. sh-HeLa cells were transfected with PHPLCδ1–RFP or the GCaMP2 sensor alone or together with GFP- or mCherry-tagged PMCA2wb. HeLa cells were co...

View article titled, Apart from its known function, the plasma membrane Ca 2+ ATPase can regulate Ca 2+ signaling by controlling phosphatidylinositol 4,5-bisphosphate levels

Includes: Supplementary data

Journal Articles

Palmitoylation is the switch that assigns calnexin to quality control or ER Ca 2+ signaling

Emily M. Lynes, Arun Raturi, Marina Shenkman, Carolina Ortiz Sandoval, Megan C. Yap, Jiahui Wu, Aleksandra Janowicz, Nathan Myhill, Matthew D. Benson, Robert E. Campbell, Luc G. Berthiaume, Gerardo Z. Lederkremer, Thomas Simmen

J Cell Sci (2013) 126 (17): 3893–3903.

DOI: https://doi.org/10.1242/jcs.125856

Published: 1 September 2013

... with FLAG-tagged wild-type or CCAA calnexin were lysed and processed for western blotting using the FLAG antibody. Fig. 4. Palmitoylated calnexin regulates ER Ca2+ signaling. (A) Measurement of cytosolic Ca2+ following thapsigargin (Tg)-mediated ER Ca2+ release. Calnexin (CNX) knockout (KO) MEFs and KO...

View article titled, Palmitoylation is the switch that assigns calnexin to quality control or ER Ca 2+ signaling

Includes: Supplementary data

Journal Articles

Niflumic acid disrupts marine spermatozoan chemotaxis without impairing the spatiotemporal detection of chemoattractant gradients

Adán Guerrero, Jesús Espinal, Christopher D. Wood, Juan M. Rendón, Jorge Carneiro, Gustavo Martínez-Mekler, Alberto Darszon

J Cell Sci (2013) 126 (6): 1477–1487.

DOI: https://doi.org/10.1242/jcs.121442

Published: 15 March 2013

... ). Discrete dynamics model for the speract-activated Ca2+ signaling network relevant to sperm motility. PLoS ONE 6 , e22619 . 10.1371/journal.pone.0022619 Espinosa F. , de la Vega-Beltrán J. L. , López-González I. , Delgado R. , Labarca P. , Darszon A. ( 1998...

View article titled, Niflumic acid disrupts marine spermatozoan chemotaxis without impairing the spatiotemporal detection of chemoattractant gradients

Includes: Supplementary data

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Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca 2+ release via IP 3 receptors

Cardiomyocyte differentiation from human induced pluripotent stem cells is delayed following knockout of Bcl-2

Localized TPC1-mediated Ca 2+ release from endolysosomes contributes to myoseptal junction development in zebrafish

Enforced tethering elongates the cortical endoplasmic reticulum and limits store-operated Ca 2+ entry

CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors

The p.E152K-STIM1 mutation deregulates Ca 2+ signaling contributing to chronic pancreatitis

TPC2-mediated Ca 2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos

Convergent Met and voltage-gated Ca 2+ channel signaling drives hypermigration of Toxoplasma -infected dendritic cells

The inactivation domain of STIM1 acts through intramolecular binding to the coiled-coil domain in the resting state

Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells

Evidence for a regulated Ca 2+ entry in proximal tubular cells and its implication in calcium stone formation

Leucine-rich repeat-containing 8B protein is associated with the endoplasmic reticulum Ca 2+ leak in HEK293 cells

Engineering mammalian cells to seek senescence-associated secretory phenotypes

A novel ATP-synthase-independent mechanism coupling mitochondrial activation to exocytosis in insulin-secreting cells

Nitric oxide mediates stretch-induced Ca 2+ oscillation in smooth muscle

TRPP2-dependent Ca 2+ signaling in dorso-lateral mesoderm is required for kidney field establishment in Xenopus

Bcl-2 binds to and inhibits ryanodine receptors

Apart from its known function, the plasma membrane Ca 2+ ATPase can regulate Ca 2+ signaling by controlling phosphatidylinositol 4,5-bisphosphate levels

Palmitoylation is the switch that assigns calnexin to quality control or ER Ca 2+ signaling

Niflumic acid disrupts marine spermatozoan chemotaxis without impairing the spatiotemporal detection of chemoattractant gradients

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