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Keywords: CK1
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Journal Articles
Journal Articles
J Cell Sci (2016) 129 (22): 4213–4226.
Published: 15 November 2016
... ). The CK1 family: contribution to cellular stress response and its role in carcinogenesis . Front. Oncol.   4 , 96 . 10.3389/fonc.2014.00096 Koh , M. Y. , Darnay , B. G. and Powis , G. ( 2008 ). Hypoxia-associated factor, a novel E3-ubiquitin ligase, binds and ubiquitinates hypoxia...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (17): 2976–2986.
Published: 1 September 2010
...)-mediated silencing of CK1δ under hypoxic conditions. Conversely, overexpression of CK1δ or phosphomimetic mutation of Ser247 to aspartate inhibited HIF-1α activity without affecting its stability or nuclear accumulation. Immunoprecipitation and in vitro binding experiments suggest that CK1-dependent...
Includes: Supplementary data
Journal Articles
J Cell Sci (2002) 115 (1): 217–226.
Published: 1 January 2002
... sequence. The phosphorylation of these residues facilitates the ubiquitination and internalization of the permease. Following endocytosis, the permease is targeted to the lysosome/vacuole for proteolysis. We have shown that in casein kinase 1 (CK1)-deficient cells, the permease is poorly phosphorylated...