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Keywords: C. elegans
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Journal Articles
Journal Articles
J Cell Sci (2022) 135 (8): jcs259025.
Published: 20 April 2022
.... Further analysis of SPD-5 and other PCM proteins will lead to a better understanding of the universality and diversity of the PCM formation mechanisms. All C. elegans strains were cultured as described ( Brenner, 1974 ). The strains used in this article are listed in Table S1 and were...
Includes: Supplementary data
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J Cell Sci (2021) 134 (24): jcs259085.
Published: 15 December 2021
... organization during recycling remain unclear. In this study, we identified a synergistic endosomal actin assembly restricting mechanism in C. elegans involving WTS-1, the homolog of LATS kinases, which is a core component of the Hippo pathway. WTS-1 resides on the sorting endosomes and colocalizes...
Includes: Supplementary data
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J Cell Sci (2021) 134 (14): jcs253088.
Published: 26 July 2021
... levels is critical. In Caenorhabditis elegans , the anaphase-promoting complex/cyclosome and its co-activator FZR-1 (APC/C FZR-1 ), a ubiquitin ligase, negatively regulates centrosome assembly through SAS-5 degradation. In this study, we report the C. elegans ZYG-1 (Plk4 in humans) as a potential...
Includes: Supplementary data
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Mechanobiology
J Cell Sci (2019) 132 (19): jcs231357.
Published: 9 October 2019
... forces during cytokinesis is not well understood. Here we show that, under mechanical stress, cortical actomyosin flow can switch polarization during cytokinesis in the C. elegans embryo. In unstressed embryos, longitudinal cortical flow contributes to contractile ring formation, while rotational...
Includes: Supplementary data
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Mitochondria
J Cell Sci (2018) 131 (22): jcs219956.
Published: 21 November 2018
... of N2 and c30F12.2(ok3505) animals; n=5 independent experiments with 10 animals per group. In C. elegans , RNAi inhibition of mitochondrial electron transport chain (ETC) genes can cause a dose- and developmental stage-dependent extension in lifespan via activation of UPRmt. However, activation...
Includes: Supplementary data
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Cytoskeleton
J Cell Sci (2018) 131 (20): jcs223107.
Published: 22 October 2018
... ( Fig. S3A ). Ciliated neurons and URX show a consistent enrichment of γ-tubulin at the base of the cilium ( Fig. S3A ), as has been reported previously ( Bobinnec et al., 2000 ). In line with these results, endogenously tagged GIP-2 (an essential subunit of the C. elegans γ-tubulin complex; Wang et...
Includes: Supplementary data
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J Cell Sci (2017) 130 (24): 4200–4212.
Published: 15 December 2017
... package, ImaEdge, automates the segmentation of the cell cortex from time-lapse movies, and enables quantitative extraction of cortical protein dynamics in cells undergoing polarization. Cortex C. elegans Zygote Polarity PAR protein Actomyosin Segmentation Image processing The cell...
Includes: Supplementary data
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J Cell Sci (2017) 130 (23): 4063–4071.
Published: 1 December 2017
... declare no competing or financial interests. 6 2 2017 23 10 2017 © 2017. Published by The Company of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Summary: Dynein and EFF-1 have a non-autonomous function in patterning PVD dendrites in C. elegans through...
Includes: Supplementary data
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J Cell Sci (2017) 130 (23): 3965–3974.
Published: 1 December 2017
..., highlighting the need for future research efforts aimed at elucidating its roles in neuronal and non-neuronal tissues. Given the identification of srGAPs as modulators of cadherin-dependent cell–cell adhesion in the C. elegans embryo ( Zaidel-Bar et al., 2010 ) and in vertebrate tissue culture ( Liang et...
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