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Keywords: Actin
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Journal Articles
J Cell Sci jcs.261057.
Published: 7 February 2024
...Thomas C. A. Blake; Helen M. Fox; Vasja Urbančič; Roshan Ravishankar; Adam Wolowczyk; Edward S. Allgeyer; Julia Mason; Gaudenz Danuser; Jennifer L. Gallop Filopodia are narrow actin-rich protrusions with important roles in neuronal development where membrane-binding adaptor proteins have emerged...
Journal Articles
J Cell Sci (2024) 137 (2): jcs261527.
Published: 26 January 2024
...Laura E. McCormick; Cristian Suarez; Laura E. Herring; Kevin S. Cannon; David R. Kovar; Nicholas G. Brown; Stephanie L. Gupton ABSTRACT The actin cytoskeleton performs multiple cellular functions, and as such, actin polymerization must be tightly regulated. We previously demonstrated...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton , Imaging
J Cell Sci (2024) 137 (2): jcs261389.
Published: 18 January 2024
...Thomas A. Phillips; Stefania Marcotti; Susan Cox; Maddy Parsons ABSTRACT The actin cytoskeleton plays a critical role in cell architecture and the control of fundamental processes including cell division, migration and survival. The dynamics and organisation of F-actin have been widely studied...
Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2023) 136 (22): jcs261667.
Published: 23 November 2023
...Matthieu Gélin; Alexandre Schaeffer; Jérémie Gaillard; Christophe Guérin; Benoit Vianay; Magali Orhant-Prioux; Marcus Braun; Christophe Leterrier; Laurent Blanchoin; Manuel Théry ABSTRACT The crosstalk between the actin network and microtubules is essential for cell polarity. It orchestrates...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (16): jcs261356.
Published: 18 August 2023
...Sabrina M. Holland; Gianluca Gallo ABSTRACT The regulation of the intracellular level of ATP is a fundamental aspect of bioenergetics. Actin cytoskeletal dynamics have been reported to be an energetic drain in developing neurons and platelets. We addressed the role of actin dynamics in primary...
Journal Articles
In collection:
Cytoskeleton , Motors
J Cell Sci (2023) 136 (10): jcs261100.
Published: 25 May 2023
..., distribution and reproduction in any medium provided that the original work is properly attributed. Highlighted Article: GIPC3 couples the molecular motors MYO6 and MYO18A to actin cytoskeleton structures in hair cells. GIPC3 is necessary for shaping cuticular plate of the hair cell and hence...
Includes: Supplementary data
Journal Articles
In collection:
Adhesion
J Cell Sci (2023) 136 (8): jcs260746.
Published: 21 April 2023
.... Actin Integrin Kindlin Membrane Talin Agence Nationale de la Recherche http://dx.doi.org/10.13039/501100001665 ANR-18-CE13-0026-01 ANR-21-CE13-0010-03 ANR-20-CE13-0016 * These authors contributed equally to this work ‡ Author for correspondence...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (8): jcs260576.
Published: 20 April 2023
...Michael Bachmann; Baihao Su; Rolle Rahikainen; Vesa P. Hytönen; Jinhua Wu; Bernhard Wehrle-Haller ABSTRACT Talin (herein referring to the talin-1 form), is a cytoskeletal adapter protein that binds integrin receptors and F-actin, and is a key factor in the formation and regulation of integrin...
Journal Articles
In collection:
Cytoskeleton , Motors
J Cell Sci (2023) 136 (5): jcs260890.
Published: 14 March 2023
...Melissa A. Quintanilla; John A. Hammer; Jordan R. Beach ABSTRACT Non-muscle myosin 2 (NM2) motors are the major contractile machines in most cell types. Unsurprisingly, these ubiquitously expressed actin-based motors power a plethora of subcellular, cellular and multicellular processes...
Includes: Supplementary data
Journal Articles
In collection:
Membrane Trafficking
J Cell Sci (2023) 136 (6): jcs260366.
Published: 5 March 2023
...Franziska Lehne; Sven Bogdan ABSTRACT Exocytosis is a fundamental cellular process by which cells secrete cargos from their apical membrane into the extracellular lumen. Cargo release proceeds in sequential steps that depend on coordinated assembly and organization of an actin cytoskeletal network...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2023) 136 (5): jcs261025.
Published: 2 March 2023
... molecular motors and other proteins are immobilized on artificial surfaces. In this Perspective, I discuss the progress towards practically viable applications achieved so far using the myosin II–actin motor–filament system. I also highlight several fundamental pieces of insights derived from the studies...
Journal Articles
In collection:
Motors , Polarity
J Cell Sci (2023) 136 (5): jcs260300.
Published: 17 October 2022
.... ( 1993 ). Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape . J. Cell Biol. 120 , 923 - 934 . 10.1083/jcb.120.4.923 Glotzer , J. B. , Saffrich , R. , Glotzer , M. and Ephrussi , A. ( 1997 ). Cytoplasmic flows localize...
Includes: Supplementary data
Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2022) 135 (19): jcs260511.
Published: 3 October 2022
...). Assembled virions accumulate in the lumen of the VCC, from where they can be released into the extracellular medium via mechanisms that remain poorly described. Here, we show that the actin cytoskeleton contributes to this process by performing experiments combining pharmacological and mechanical...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2022) 135 (16): jcs259993.
Published: 26 August 2022
... tension control is thus essential for understanding cell morphogenesis. Increasing evidence shows that alongside myosin activity, actin network organisation and composition are key to cortex tension regulation. However, owing to a poor understanding of how cortex composition changes when tension changes...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2022) 135 (13): jcs259692.
Published: 4 July 2022
... in the presence of dynamic F-actin exhibit a striking bilobed nuclear morphology with distinct membrane compositions in the two lobes and accumulation of F-actin at the inner nuclear envelope. The addition of Lamin A (encoded by lmna ), which is absent from Xenopus eggs, results in rounder nuclei, suggesting...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2022) 135 (10): jcs259030.
Published: 16 May 2022
... on the cell-type-specific mechanisms regulating ciliogenesis at the apical surface in polarized epithelial cells, which are particularly relevant for many ciliopathies. Furthermore, recent findings have demonstrated the importance of actin cytoskeleton dynamics in positively and negatively regulating multiple...