1-20 of 312
Keywords: Actin
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci jcs.259623.
Published: 15 June 2022
... in this mechanism of actin, Rho GTPases and microtubules, which are major actors of CIE processes. We show that the actin cytoskeleton is dynamically associated with endoA3- and CD166-positive endocytic carriers and that its perturbation strongly inhibits the uptake process of CD166. We also reveal that the Rho...
Journal Articles
J Cell Sci jcs.259692.
Published: 6 June 2022
... in the presence of dynamic F-actin exhibit a striking bilobed nuclear morphology with distinct membrane compositions in the two lobes and accumulation of F-actin at the inner nuclear envelope. Absent from Xenopus eggs, Lamin A addition results in rounder nuclei, suggesting that opposing nuclear F-actin and Lamin...
Journal Articles
J Cell Sci (2022) 135 (10): jcs259042.
Published: 27 May 2022
...Hendrik Schürmann; Fatemeh Abbasi; Antonella Russo; Arne D. Hofemeier; Matthias Brandt; Johannes Roth; Thomas Vogl; Timo Betz ABSTRACT Podosomes are mechanosensitive protrusive actin structures that are prominent in myeloid cells, and they have been linked to vascular extravasation. Recent studies...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (10): jcs259030.
Published: 16 May 2022
... on the cell-type-specific mechanisms regulating ciliogenesis at the apical surface in polarized epithelial cells, which are particularly relevant for many ciliopathies. Furthermore, recent findings have demonstrated the importance of actin cytoskeleton dynamics in positively and negatively regulating multiple...
Journal Articles
In collection:
Cytoskeleton , Imaging
J Cell Sci (2022) 135 (7): jcs259234.
Published: 8 April 2022
...Joseph Atherton; Melissa Stouffer; Fiona Francis; Carolyn A. Moores ABSTRACT Neurons extend axons to form the complex circuitry of the mature brain. This depends on the coordinated response and continuous remodelling of the microtubule and F-actin networks in the axonal growth cone. Growth cone...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2022) 135 (1): jcs258850.
Published: 10 January 2022
... ABSTRACT Septins, a family of GTP-binding proteins that assemble into higher order structures, interface with the membrane, actin filaments and microtubules, and are thus important regulators of cytoarchitecture. Septin 9 (SEPT9), which is frequently overexpressed in tumors and mutated in hereditary...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (24): jcs259237.
Published: 20 December 2021
...Anne Bourdais; Benoit Dehapiot; Guillaume Halet ABSTRACT How multiple actin networks coexist in a common cytoplasm while competing for a shared pool of monomers is still an ongoing question. This is exemplified by meiotic maturation in the mouse oocyte, which relies on the dynamic remodeling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (24): jcs259085.
Published: 15 December 2021
...Hanchong Zhang; Zihang Cheng; Wenbo Li; Jie Hu; Linyue Zhao; Dan Chen; Jinghu Gao; Juan Chen; Yanling Yan; Long Lin; Anbing Shi ABSTRACT The disruption of endosomal actin architecture negatively affects endocytic recycling. However, the underlying homeostatic mechanisms that regulate actin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (23): jcs258891.
Published: 9 December 2021
... finally tested whether a phosphomimetic WAVE SD mutant of the VCA domain exhibits a higher protein stability or actin polymerization activity in vivo . Here, we used the Drosophila wing imaginal disc as an in vivo model to measure the effect of the WAVE overexpression. We used the en -Gal4 driver...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (23): jcs258802.
Published: 6 December 2021
...Marie-Thérèse Prospéri; Julien Pernier; Hugo Lachuer; Evelyne Coudrier ABSTRACT EphB2–ephrinB signalling, which plays a major role in cell segregation during embryonic development and tissue homeostasis, induces an important reorganization of the cortical actin network. We have previously reported...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (21): jcs258973.
Published: 5 November 2021
... function for the distribution of F-actin plus and minus ends. In syncytial Drosophila embryos, Rho1 signaling is high between actin caps, i.e. the cortical intercap region. Capping protein binds to free plus ends of F-actin to prevent elongation of the filament. Capping protein has served as a marker...
Includes: Supplementary data
Journal Articles
In collection:
Polarity
J Cell Sci (2021) 134 (20): jcs258523.
Published: 18 October 2021
... by The Company of Biologists Ltd 2021 Summary: The LLxY motif in the C-terminal region of ATP11C-b, a phosphatidylserine flippase, is crucial for its interaction with ezrin, as well as its polarized localization in motile cells. Actin Biological membrane Ezrin Flippase Polarization...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (14): jcs254011.
Published: 19 July 2021
...Caitlin C. Devitt; Chanjae Lee; Rachael M. Cox; Ophelia Papoulas; José Alvarado; Shashank Shekhar; Edward M. Marcotte; John B. Wallingford ABSTRACT The dynamic control of the actin cytoskeleton is a key aspect of essentially all animal cell movements. Experiments in single migrating cells...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (12): jcs244384.
Published: 21 June 2021
...Nicholas V. G. Iannantuono; Gregory Emery ABSTRACT Cytokinesis occurs at the end of mitosis/meiosis wherein the cytoplasms of daughter cells are separated. Before abscission, an intercellular bridge containing the remaining furrowing machinery, mitotic spindle and actin cytoskeleton connects...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (9): jcs249060.
Published: 7 May 2021
...Abigail Allen; David Gau; Partha Roy ABSTRACT Dynamic remodeling of the actin cytoskeleton is an essential feature for virtually all actin-dependent cellular processes, including cell migration, cell cycle progression, chromatin remodeling and gene expression, and even the DNA damage response...
Journal Articles
J Cell Sci (2021) 134 (7): jcs226084.
Published: 13 April 2021
... with mitochondria – the actin-based myosins, as well as the microtubule-based kinesins and dynein. In addition, Miro and TRAK proteins act as adaptors that link kinesin-1 and dynein, as well as myosin of class XIX (MYO19), to mitochondria and coordinate microtubule- and actin-based motor activities. Here, we...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (6): jcs253021.
Published: 26 March 2021
... cell tip, and weakest when the nucleus is far from that tip. Microtubule-independent nuclear movement requires actin cables but does not depend on actin polymerization-based pushing or myosin V-based pulling forces. The vesicle-associated membrane protein (VAMP)-associated proteins (VAPs) Scs2...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (5): jcs251298.
Published: 25 February 2021
... disease. Appressorium functionality is dependent on the formation of a cortical septin ring during its morphogenesis, but precisely how this structure assembles is unclear. Here, we show that F-actin rings are recruited to the circumference of incipient septin disc-like structures in a pressure-dependent...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (4): jcs246496.
Published: 17 February 2021
... play an important role in cellular function and morphology. The biophysical properties of cells and tissues are determined by the cytoskeleton, consisting of dynamic networks of F-actin and microtubules, molecular motors, crosslinkers and other associated proteins, among other factors such as cell–cell...
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (3): jcs248385.
Published: 8 February 2021
...Gillian DeWane; Alicia M. Salvi; Kris A. DeMali ABSTRACT Attention has long focused on the actin cytoskeleton as a unit capable of organizing into ensembles that control cell shape, polarity, migration and the establishment of intercellular contacts that support tissue architecture. However...