CELL SCIENTISTS TO WATCH
Summary: A Review of ubiquitylation and its biochemical relatives as regulators of the endolysosomal system and its hijacking by intracellular bacteria in order for them to prosper inside cells.
Field model for multistate lateral diffusion of various transmembrane proteins observed in living Dictyostelium cells
Summary: The complex diffusion behaviors of various transmembrane proteins in Dictyostelium cells can be explained quantitatively by free diffusion on three membrane regions of different viscosities.
Summary: Chromosome compaction depends on the cell cycle and the chromosome arm. In vivo, chromatin dynamics, which are modulated by transcription and interactions between chromatin and nuclear landmarks, are genomic-locus specific.
Lamin A/C phosphorylation at serine 22 is a conserved heat shock response to regulate nuclear adaptation during stress
Highlighted Article: Phosphorylation of nuclear lamin A/C at Ser22 is an evolutionarily conserved mechanism that regulates lamin dynamics to serve nuclear adaptation and cell survival in heat-shocked cells.
Highlighted Article: Nucleolar architecture is altered during myogenic differentiation, indicating that the phase separation properties and function of the nucleolus might change during myogenesis.
Toxoplasma gondii scavenges mammalian host organelles through the usurpation of host ESCRT-III and Vps4A
Summary: The parasitophorous vacuole of Toxoplasma gondii sequesters host organelles by utilizing TgGRA14 and TgGRA64, which interact with host ESCRT proteins for vacuolar membrane remodeling and fission.
Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via IP3 receptors
Highlighted Article: The C-terminal region of Jaw1, a tail-anchored protein, is cleaved by the signal peptidase complex and this cleavage event enhances the augmentative effect of Jaw1 on the Ca2+ release activity of inositol 1,4,5-trisphosphate receptors.
TOOLS AND RESOURCES
Summary: Fast4DReg is an open-source Fiji plugin that can quickly correct axial and lateral drift in multidimensional microscopy datasets.