Cover: a polyp of the cnidarian Hydractinia echinata showing acetylated tubulin (green), F-actin (red) and DNA (blue). Manipulating the expression of Nanos2 interferes with the fate of early neural progenitors, disrupting the balance between two distinct cell lineages in the nervous system of the animal. Image by R. C. Millane. See article by J. Kanska and U. Frank (pp. 3192–3203).
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Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle – pivotal roles in Ca2+ and reactive oxygen species signaling
Preferential invasion of mitotic cells by Salmonella reveals that cell surface cholesterol is maximal during metaphase
Phosphorylation of Gβ is crucial for efficient chemotropism in yeast
New roles of the fission yeast eIF2α kinases Hri1 and Gcn2 in response to nutritional stress
Vinculin tension distributions of individual stress fibers within cell–matrix adhesions
Plakoglobin interacts with the transcription factor p53 and regulates the expression of 14-3-3σ
Poly(lactide-co-glycolide)-rifampicin nanoparticles efficiently clear Mycobacterium bovis BCG infection in macrophages and remain membrane-bound in phago-lysosomes
PfSec13 is an unusual chromatin-associated nucleoporin of Plasmodium falciparum that is essential for parasite proliferation in human erythrocytes
Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance
Antagonism and synergy between extracellular BMP modulators Tsg and BMPER balance blood vessel formation
Ku70 and non-homologous end joining protect testicular cells from DNA damage
Lamin aggregation is an early sensor of porphyria-induced liver injury
A mechanism of gap junction docking revealed by functional rescue of a human-disease-linked connexin mutant
Drosophila TRP and TRPL are assembled as homomultimeric channels in vivo
Evidence for a radial SNARE super-complex mediating neurotransmitter release at the Drosophila neuromuscular junction
Intermolecular disulfide bonds between nucleoporins regulate karyopherin-dependent nuclear transport
Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity
A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function
Phosphorylation of STIM1 at ERK1/2 target sites regulates interaction with the microtubule plus-end binding protein EB1
Pbx1 restrains myeloid maturation while preserving lymphoid potential in hematopoietic progenitors
New roles for Nanos in neural cell fate determination revealed by studies in a cnidarian
Germline deletion of Cetn1 causes infertility in male mice
Histone H3 phosphorylation and elimination of paternal X chromosomes at early cleavages in sciarid flies
Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication
ARTICLE OF INTEREST IN OTHER COB JOURNALS
Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity
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