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Volume 125, Issue 1
January 2012
Issue Cover
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  • Cover image

    Cover Image

    issue cover
    Cover: Confocal micrograph showing the follicular epithelium of a Drosophila egg chamber marked for α-Spectrin (magenta) and GFP (green). GFP-positive cells lack α-Catenin and instead express a DE-Cadherin::α-Catenin fusion protein, which rescues the adhesion defects that would otherwise arise from the loss of α-Catenin. See article by R. Sarpal et al. (pp. 233-245).
  • PDF Icon PDF LinkTable of contents
ISSN 0021-9533
EISSN 1477-9137

EDITORIAL

A fresh start – but business as usual
View articletitled, A fresh start – but business as usual
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STICKY WICKET

When conflicted becomes corrupted II – the Molette doctrine
Molette
View articletitled, When conflicted becomes corrupted II – the Molette doctrine
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COMMENTARY

MicroRNAs and their roles in aging
Thalyana Smith-Vikos,Frank J. Slack
View articletitled, MicroRNAs and their roles in aging
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The role of clathrin in mitotic spindle organisation
Stephen J. Royle
View articletitled, The role of clathrin in mitotic spindle organisation
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SHORT REPORT

The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
Viola Hélène Lobert,Harald Stenmark
View articletitled, The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
Supplementary information
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RESEARCH ARTICLE

TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing
Daniel Rosel,Taruna Khurana,Amit Majithia,Xiuli Huang,Ramanath Bhandari,Alan R. Kimmel
View articletitled, TOR complex 2 (TORC2) in <em>Dictyostelium</em> suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing
Supplementary information
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A conserved membrane-binding domain targets proteins to organelle contact sites
Alexandre Toulmay,William A. Prinz
View articletitled, A conserved membrane-binding domain targets proteins to organelle contact sites
Supplementary information
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Loss of Scribble causes cell competition in mammalian cells
Mark Norman,Katarzyna A. Wisniewska,Kate Lawrenson,Pablo Garcia-Miranda,Masazumi Tada,Mihoko Kajita,Hiroki Mano,Susumu Ishikawa,Masaya Ikegawa,Takashi Shimada,Yasuyuki Fujita
View articletitled, Loss of Scribble causes cell competition in mammalian cells
Supplementary information
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Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP
Joongkyu Park,Jee Young Sung,Joohyun Park,Woo-Joo Song,Sunghoe Chang,Kwang Chul Chung
View articletitled, Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP
Supplementary information
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Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1
Wei Gu,Zachary Katz,Bin Wu,Hye Yoon Park,Deling Li,Stanley Lin,Amber L. Wells,Robert H. Singer
View articletitled, Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1
Supplementary information
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Annexin A5 stimulates autophagy and inhibits endocytosis
Ghita Ghislat,Carmen Aguado,Erwin Knecht
View articletitled, Annexin A5 stimulates autophagy and inhibits endocytosis
Supplementary information
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Liprin-α controls stress fiber formation by binding to mDia and regulating its membrane localization
Satoko Sakamoto,Toshimasa Ishizaki,Katsuya Okawa,Sadanori Watanabe,Takatoshi Arakawa,Naoki Watanabe,Shuh Narumiya
View articletitled, Liprin-α controls stress fiber formation by binding to mDia and regulating its membrane localization
Supplementary information
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Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repair
Christopher G. Elliott,Jian Wang,Xiaolei Guo,Shi-wen Xu,Mark Eastwood,Jianjun Guan,Andrew Leask,Simon J. Conway,Douglas W. Hamilton
View articletitled, Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repair
Supplementary information
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The MCM-associated protein MCM-BP is important for human nuclear morphology
Madhav Jagannathan,Amos M. Sakwe,Tin Nguyen,Lori Frappier
View articletitled, The MCM-associated protein MCM-BP is important for human nuclear morphology
Supplementary information
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The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export
Inga Waldmann,Christiane Spillner,Ralph H. Kehlenbach
View articletitled, The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export
Supplementary information
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Quantitative mapping of averaged focal adhesion dynamics in migrating cells by shape normalization
Christoph Möhl,Norbert Kirchgessner,Claudia Schäfer,Bernd Hoffmann,Rudolf Merkel
View articletitled, Quantitative mapping of averaged focal adhesion dynamics in migrating cells by shape normalization
Supplementary information
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The integrator complex is required for integrity of Cajal bodies
Hideaki Takata,Hitoshi Nishijima,Kazuhiro Maeshima,Kei-ichi Shibahara
View articletitled, The integrator complex is required for integrity of Cajal bodies
Supplementary information
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Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation
Ana del Puerto,Juan-Ignacio Díaz-Hernández,Mónica Tapia,Rosa Gomez-Villafuertes,María José Benitez,Jin Zhang,María Teresa Miras-Portugal,Francisco Wandosell,Miguel Díaz-Hernández,Juan José Garrido
View articletitled, Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation
Supplementary information
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Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability
Ramya Kumareswaran,Olga Ludkovski,Alice Meng,Jenna Sykes,Melania Pintilie,Robert G. Bristow
View articletitled, Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability
Supplementary information
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Soluble molecules are key in maintaining the immunomodulatory activity of murine mesenchymal stromal cells
Hua Liu,Kai Lu,Paul Anthony MacAry,Kok Loon Wong,Alexis Heng,Tong Cao,David Michael Kemeny
View articletitled, Soluble molecules are key in maintaining the immunomodulatory activity of murine mesenchymal stromal cells
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Cdt1p, through its interaction with Mcm6p, is required for the formation, nuclear accumulation and chromatin loading of the MCM complex
Rentian Wu,Jiafeng Wang,Chun Liang
View articletitled, Cdt1p, through its interaction with Mcm6p, is required for the formation, nuclear accumulation and chromatin loading of the MCM complex
Supplementary information
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Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase
Peristera Roboti,Stephen High
View articletitled, Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase
Supplementary information
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Mutational analysis supports a core role for Drosophila α-Catenin in adherens junction function
Ritu Sarpal,Milena Pellikka,Ridhdhi R. Patel,Felix Yan Wai Hui,Dorothea Godt,Ulrich Tepass
View articletitled, Mutational analysis supports a core role for <em>Drosophila</em> α-Catenin in adherens junction function
Supplementary information
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CORRECTION

CRSBP-1/LYVE-1 ligands disrupt lymphatic intercellular adhesion by inducing tyrosine phosphorylation and internalization of VE-cadherin
Wei-Hsien Hou,I-Hua Liu,Cheng C. Tsai,Frank E. Johnson,Shuan Shian Huang,Jung San Huang
View articletitled, CRSBP-1/LYVE-1 ligands disrupt lymphatic intercellular adhesion by inducing tyrosine phosphorylation and internalization of VE-cadherin
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ARTICLE OF INTEREST IN OTHER COB JOURNALS

FROM DEVELOPMENT
A model of stem cell population dynamics: in silico analysis and in vivo validation
Yaki Setty,Diana Dalfó,Dorota Z. Korta,E. Jane Albert Hubbard,Hillel Kugler
View articletitled, A model of stem cell population dynamics: in silico analysis and in vivo validation
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Drosophila G-protein-coupled receptor kinase 2 regulates cAMP-dependent Hedgehog signalling
Shuofei Cheng,Dominic Maier,David R. Hipfner
View articletitled, <em>Drosophila</em> G-protein-coupled receptor kinase 2 regulates cAMP-dependent Hedgehog signalling
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IN THIS ISSUE

Competition as a tumour suppressor?
View articletitled, Competition as a tumour suppressor?
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α-Catenin function stays at the junction
View articletitled, α-Catenin function stays at the junction
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New way to stop N-WASP
View articletitled, New way to stop N-WASP
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Cajal bodies: no integrity without integrator
View articletitled, Cajal bodies: no integrity without integrator
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Liprin-α and actin remodelling
View articletitled, Liprin-α and actin remodelling
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ADCY5 acts as neuronal signal coordinator
View articletitled, ADCY5 acts as neuronal signal coordinator
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Accepted manuscripts
DEK oncoprotein participates in heterochromatin replication via SUMO-dependent nuclear bodies
Agnieszka Pierzynska-Mach, Christina Czada, Christopher Vogel, Eva Gwosch, Xenia Osswald, Denis Bartoschek, Alberto Diaspro, Ferdinand Kappes, Elisa Ferrando-May
AP-1 signaling modulates cardiac fibroblast stress responses
Alexander J. Whitehead, Hamza Atcha, James D. Hocker, Bing Ren, Adam J. Engler
Cellular responses to compound stress induced by atmospheric-pressure plasma in fission yeast
Yoko Otsubo, Akira Yamashita, Yuhei Goto, Keiichiro Sakai, Tetsushi Iida, Shinji Yoshimura, Katsuki Johzuka
Cell jamming in a collagen-based interface assay: tuning by collagen density and proteolysis
Lianne Beunk, Nan Wen, Sjoerd van Helvert, Bram Bekker, Lars Ran, Ross Kang, Tom Paulat, Simon Syga, Andreas Deutsch, Peter Friedl, Katarina Wolf
Identification of distinct active pools of yeast serine palmitoyltransferase in sub-compartments of the ER
Bianca M. Esch, Stefan Walter, Oliver Schmidt, Florian Fröhlich
More accepted manuscripts

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