Revealing the nanoscale morphology of the primary cilium using super-resolution fluorescence microscopy by Yoon et al.
Lighting up the cell's antenna: beyond the diffraction limit, the primary cilium doesn't look quite like a cylinder.
Selected by Gautam Dey. Read the preLight here
Tension on kinetochore substrates is insufficient to prevent Aurora-triggered detachment by de Regt et al.
What tension? Pulling forces in a proper bi-polar spindle are thought to turn off Aurora B-directed corrections. An in vitro study suggests that tension on kinetochores alone cannot deter this kinase.
Selected by Angika Basant. Read the preLight here
Molecular organization of integrin-based adhesion complexes in mouse Embryonic Stem Cells by Xia et al.
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Superresolution architecture of pluripotency guarding adhesions by Stubb et al.
Stem cell focal adhesions are structurally different to those of differentiated cells and maintain pluripotency.
Selected by Nicola Stevenson and Amanda Haage. Read the preLight here
Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain (AL) amyloidosis patient by Swuec et al.
Zooming in on protein misfolding diseases - the first high-resolution structure of patient-derived light chain amyloid fibrils revealed.
Selected by Tessa Sinnige. Read the preLight here
Lysosome exocytosis is required for mitosis by Nugues et al.
How do cells remodel their membrane when undergoing mitosis? A recent preprint shows that lysosome exocytosis is needed for correct cell division.
Selected by Claudia Conte. Read the preLight here
Bridging the divide: bacteria synthesizing archaeal membrane lipids by Villanueva et al.
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Extensive transfer of membrane lipid biosynthetic genes between Archaea and Bacteria by Coleman et al.
Straddling the lipid divide: evidence that archaea and bacteria have exchanged lipid biosynthesis genes in the past, and that a present-day Black Sea bacterium might possess a mixed membrane.
Selected by Gautam Dey. Read the preLight here
Evidence for an Integrated Gene Repression Mechanism based on mRNA Isoform Toggling in Human Cells by Hollerer et al.
Toggling promoters and open reading frames to regulate gene expression.
Selected by Clarice Hong. Read the preLight here
Actomyosin-driven tension at compartmental boundaries orients cell division independently of cell geometry in vivo by Scarpa et al.
The century old Hertwig's rule in doubt: is the long cell axis rule valid in tissues?
Selected by Ivana Viktorinova. Read the preLight here
Single-cell RNA sequencing reveals novel cell differentiation dynamics during human airway epithelium regeneration by Garcia et al.
By single cell RNA sequencing airway epithelial cells during their differentiation from basal progenitor cells to mature epithelial cell types, the authors of this preprint throw light on the step-wise differentiation of the respiratory epithelium.
Comparative analysis of droplet-based ultra-high-throughput single-cell RNA-seq systems by Zhang et al.
Dropping some knowledge: A systematic comparison of droplet-based single-cell RNA-seq techniques.
Selected by Samantha Seah. Read the preLight here
PlotsOfData - a web app for visualizing data together with its summaries by Postma and Goedhart
Plot all your data with PlotsOfData
Selected by Guillaume Jacquemet. Read the preLight here
