... into the circulation. This was associated with a neutrophil-dependent expansion of systemic CD4 + T cells. Thus, our results indicate that PFOS worsens inflammation-induced intestinal damage with disruption of T-cell homeostasis beyond the gut and provides a novel in vivo toolbox to screen for pollutants affecting...

... Multiple sclerosis Central nervous system Cellular traffic T cell Adjuvant Multiple sclerosis (MS) is a disease of the central nervous system (CNS) that leads to chronic inflammation, demyelination, and axonal and neuronal loss, resulting in disability ( Noseworthy et al., 2000 ; Weissert...

...Michaela Sharpe; Natalie Mount Tumours use many strategies to evade the host immune response, including downregulation or weak immunogenicity of target antigens and creation of an immune-suppressive tumour environment. T cells play a key role in cell-mediated immunity and, recently, strategies...