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Keywords: T cell
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Journal Articles
Dis Model Mech (2021) 14 (12): dmm049104.
Published: 23 December 2021
... into the circulation. This was associated with a neutrophil-dependent expansion of systemic CD4 + T cells. Thus, our results indicate that PFOS worsens inflammation-induced intestinal damage with disruption of T-cell homeostasis beyond the gut and provides a novel in vivo toolbox to screen for pollutants affecting...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2016) 9 (10): 1211–1220.
Published: 1 October 2016
... Multiple sclerosis Central nervous system Cellular traffic T cell Adjuvant Multiple sclerosis (MS) is a disease of the central nervous system (CNS) that leads to chronic inflammation, demyelination, and axonal and neuronal loss, resulting in disability ( Noseworthy et al., 2000 ; Weissert...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2015) 8 (4): 337–350.
Published: 1 April 2015
...Michaela Sharpe; Natalie Mount Tumours use many strategies to evade the host immune response, including downregulation or weak immunogenicity of target antigens and creation of an immune-suppressive tumour environment. T cells play a key role in cell-mediated immunity and, recently, strategies...