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Keywords: Oligoclonal
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Journal Articles
In collection:
The RAS Pathway
Dis Model Mech (2022) 15 (2): dmm048887.
Published: 11 August 2021
... a confined space for growth of a distinct tumor phenotype. Lineage tracing revealed oligoclonal tumor development in infancy and early selection of BRAFV600E kinase inhibitor-resistant clones. Somatic mutations were few, non-recurrent and limited to advanced tumors. Female mice developed larger tumors than...
Includes: Supplementary data