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Keywords: Nrf2
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Journal Articles
Dis Model Mech (2022) 15 (4): dmm049235.
Published: 13 April 2022
...Vy Ngo; Anne Brickenden; Hansen Liu; Cynthia Yeung; Wing-Yiu Choy; Martin L. Duennwald ABSTRACT Nrf2 is the master transcriptional regulator of cellular responses against oxidative stress. It is chiefly regulated by Keap1, a substrate adaptor protein that mediates Nrf2 degradation. Nrf2 activity...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2020) 13 (5): dmm042648.
Published: 1 June 2020
.... Here, we show that genetic activation of the transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nfe2l2/Nrf2) in keratinocytes of Spink5 knockout mice, a model for Netherton syndrome, significantly alleviates their cutaneous phenotype. Nrf2 activation promoted attachment of the stratum...
Includes: Supplementary data
Journal Articles