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Keywords: Notochord
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Journal Articles
Dis Model Mech (2021) 14 (3): dmm047001.
Published: 19 March 2021
...Paco López-Cuevas; Luke Deane; Yushi Yang; Chrissy L. Hammond; Erika Kague ABSTRACT Notochordal cells play a pivotal role in vertebral column patterning, contributing to the formation of the inner architecture of intervertebral discs (IVDs). Their disappearance during development has been...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2019) 12 (7): dmm039545.
Published: 16 July 2019
... transformed notochord remnants. Several potentially oncogenic factors have been found to be deregulated in chordoma, yet causation remains uncertain. In particular, sustained expression of TBXT – encoding the notochord regulator protein brachyury – is hypothesized as a key driver of chordoma, yet experimental...
Includes: Supplementary data