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Keywords: NF-κB
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Journal Articles
Dis Model Mech (2023) 16 (4): dmm049965.
Published: 26 April 2023
... downstream of Toll and Imd NF-κB pathways upon infection. Upon aging, AMPs are upregulated, drawing attention to these molecules as possible causes of age-associated inflammatory diseases. However, functional studies overexpressing or silencing these genes have been inconclusive. Using an isogenic set of AMP...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2019) 12 (3): dmm037697.
Published: 4 March 2019
... lymphoma 3 (BCL-3; a key regulator of NF-κB signalling) has been recognised as an important oncogenic player in solid tumours. Although reported to be overexpressed in a subset of colorectal cancers (CRCs), the role of BCL-3 expression in colorectal tumorigenesis remains poorly understood. Despite evidence...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2015) 8 (2): 169–181.
Published: 1 February 2015
...Daniel Bandarra; John Biddlestone; Sharon Mudie; H.-Arno J. Müller; Sonia Rocha Hypoxia and inflammation are intimately linked. It is known that nuclear factor κB (NF-κB) regulates the hypoxia-inducible factor (HIF) system, but little is known about how HIF regulates NF-κB. Here, we show that HIF...
Includes: Supplementary data