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Keywords: Embryo
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Journal Articles
Dis Model Mech (2021) 14 (6): dmm049012.
Published: 17 June 2021
... in gastrulation-stage embryos from two commonly used, genetically similar mouse substrains, C57BL/6J (6J) and C57BL/6NHsd (6N), that differ in alcohol sensitivity. First, we established normal gene expression patterns at three finely resolved time points during gastrulation and developed a web-based interactive...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2018) 11 (10): dmm034637.
Published: 19 October 2018
... into the right and non-coronary leaflet. Genetic lineage tracing of endothelial, second heart field and neural crest cells revealed altered deposition of neural crest cells and second heart field cells within the parietal outflow tract cushion of Nos3 −/− embryos. The abnormal cell lineage distributions also...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2018) 11 (3): dmm032219.
Published: 21 March 2018
... and resulted in caudal spina bifida in 67% of Grhl3 Cre/+ Vangl2 Fl/Fl embryos. In the dorsal SE, Vangl2 deletion diminished rostrocaudal cell body orientation, but not directional polarisation of cell divisions. In the PNP, Vangl2 disruption diminished mediolateral polarisation of apical neuroepithelial F...
Includes: Supplementary data