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Keywords: Ecdysone
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Journal Articles
Dis Model Mech (2022) 15 (1): dmm049160.
Published: 26 January 2022
... of the prothoracic gland (PG), which controls metamorphosis onset through ecdysone production. Reducing JAK/STAT signaling decreased PG size and advanced metamorphosis. Conversely, JAK/STAT hyperactivation by overexpression of pathway components or SUMOylation loss caused PG hypertrophy and metamorphosis delay...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2020) 13 (6): dmm041301.
Published: 24 June 2020
... of its canonical mineralocorticoid receptor. Here, we present a Drosophila model of renal pathology caused by excess extracellular matrix formation, stimulated by exogenous aldosterone and by insect ecdysone. Chronic administration of aldosterone or ecdysone induces expression and accumulation...
Includes: Supplementary data