... differentiation. Finally, patients affected by COL6-related myopathies were evaluated with an ad hoc neuropsychological protocol, revealing distinctive defects in attentional control abilities. Altogether, these findings point towards a previously undescribed role for COL6 in the proper maintenance of dopamine...

... test significances indicated in the graph; Fig. 1 E] flashes. Monoamine oxidases catalyze the oxidative deamination of several endogenous and dietary amines, including dopamine (DA), norepinephrine (NE), serotonin (5-HT) and the first histamine metabolite, tele-N-methylhistamine. In mammals...

... that indicate the above abnormalities. Compared to vehicle, rotenone reduced locomotor activity ( P =0.002), decreased tissue dopamine concentrations ( P =0.00001), reduced indices of vesicular sequestration (3,4-dihydroxyphenylacetic acid (DOPAC)/dopamine) and ALDH activity (DOPAC/DOPAL) ( P =0.0025, P =0.036...

.... The healthy striatum was metabolically connected to the ipsilesional substantia nigra in hemiparkinsonian rats only (OFF condition). STN-DBS (ON condition) established a new functional striatal network, in which interhemispheric striatal connectivity was strengthened, and both the dopamine-depleted...

... and dopamine receptors induced robust and sometimes complex concentration-dependent effects on schistosome motility and length; in some cases, these effects occurred at concentrations achievable in vivo . The present data advance our knowledge of the organization of the nervous system in this globally...

...-dopamine (6-OHDA) in rat parkinsonian models. Recently, we investigated the molecular background of the neuroprotective effect of PACAP in dopamine (DA)-based neurodegeneration using rotenone-induced snail and 6-OHDA-induced rat models of Parkinson's disease. Behavioural activity, monoamine (DA...