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Keywords: Development
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Journal Articles
In collection:
The RAS Pathway
Dis Model Mech (2022) 15 (2): dmm048887.
Published: 11 August 2021
... differentiation ( Liang et al., 2018 ). It is assumed that segregation of cells with different growth properties during development generates follicles of different size and tissue distribution in the adult gland ( Nilsson and Fagman, 2013 ). Developmental trajectories that govern follicle heterogeneity might...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2020) 13 (12): dmm046920.
Published: 21 December 2020
... of imaging analyses has enabled the discovery of dynamic migratory behaviors of PNECs during airway development, perhaps relating to SCLC malignancy. This Review summarizes the findings from research on PNECs, along with novel knowledge about their function. In addition, it thoroughly addresses the relevant...
Journal Articles
Dis Model Mech (2020) 13 (9): dmm044990.
Published: 28 September 2020
... ). The aorta and the aortic valve have a similar developmental origin involving contributions of endothelial, NCC and second heart field lineages. BAV patients have increased risk of developing aneurysms and dissections of the ascending aorta but not of the descending aorta ( Biner et al., 2009 ). NCCs...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2018) 11 (10): dmm034637.
Published: 19 October 2018
... to be significantly different ( P <0.05), indicating that the underlying changes in cell distribution may also affect annulus formation in tricuspid Nos3 −/− mice. Patients with a BAV are at an increased risk of developing aortopathy. The great vessels and the aortic valve have a similar developmental...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2016) 9 (3): 347–359.
Published: 01 March 2016
... tests. We thank Evelyn Brown and Margaret Gondo for excellent technical assistance in preparing and imaging tissue samples for electron microscopy. The slow and embryonic MyHC monoclonal antibodies used in this study were developed by H. M. Blau and were obtained from the Developmental Studies Hybridoma...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2015) 8 (5): 429–441.
Published: 01 May 2015
... cells of the sympathetic nervous system, it could represent a cancer driven by a failure in the normal developmental programme. Understanding normal mechanisms that are involved in sympathetic noradrenergic neuron development could give insight into NB pathogenesis and might suggest new approaches...
Includes: Supplementary data