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Keywords: Colitis
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Journal Articles
Dis Model Mech (2021) 14 (12): dmm049104.
Published: 23 December 2021
... interrogated the immunomodulatory effects of polyfluoroalkyl substances, which have been positively associated with ulcerative colitis incidence. Exposure to perfluorooctanesulfonic acid (PFOS) during 2,4,6-trinitro-benzene sulfonic acid (TNBS)-induced inflammation enhanced the expression of proinflammatory...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2018) 11 (7): dmm033241.
Published: 30 July 2018
..., in which HIF-1α and HIF-2α are constitutively activated in myeloid cells, we found that these mice were highly susceptible to DSS-induced colitis, demonstrating greater body weight loss, increased mortality, faster onset of rectal bleeding, shortened colon length, and increased CD11b- or Gr-1-positive...
Journal Articles
Dis Model Mech (2015) 8 (8): 805–815.
Published: 1 August 2015
... function contributes to multiple gastrointestinal disorders, including food hypersensitivity, inflammatory bowel disease (IBD) and colitis-associated cancer (CAC). Glycoprotein A33 (GPA33) is an intestinal epithelium-specific cell surface marker and member of the CTX group of transmembrane proteins. Roles...
Includes: Supplementary data