Search Results | Disease Models & Mechanisms

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Journal Articles

Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis

Frederick S. Kaplan, Salin A. Chakkalakal, Eileen M. Shore

Dis Model Mech (2012) 5 (6): 756–762.

DOI: https://doi.org/10.1242/dmm.010280

Published: 1 November 2012

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Journal Articles

Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models

Jinsong Hu, Els Van Valckenborgh, Eline Menu, Elke De Bruyne, Karin Vanderkerken

Dis Model Mech (2012) 5 (6): 763–771.

DOI: https://doi.org/10.1242/dmm.008961

Published: 1 November 2012

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Journal Articles

Role of resting metabolic rate and energy expenditure in hunger and appetite control: a new formulation

John E. Blundell, Phillipa Caudwell, Catherine Gibbons, Mark Hopkins, Erik Naslund, Neil King, Graham Finlayson

Dis Model Mech (2012) 5 (5): 608–613.

DOI: https://doi.org/10.1242/dmm.009837

Published: 1 September 2012

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Journal Articles

Obesity and psychotic disorders: uncovering common mechanisms through metabolomics

Matej Orešič

Dis Model Mech (2012) 5 (5): 614–620.

DOI: https://doi.org/10.1242/dmm.009845

Published: 1 September 2012

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Journal Articles

Anti-obesity drugs: past, present and future

R. John Rodgers, Matthias H. Tschöp, John P. H. Wilding

Dis Model Mech (2012) 5 (5): 621–626.

DOI: https://doi.org/10.1242/dmm.009621

Published: 1 September 2012

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Journal Articles

Putting together the psoriasis puzzle: an update on developing targeted therapies

Leanne M. Johnson-Huang, Michelle A. Lowes, James G. Krueger

Dis Model Mech (2012) 5 (4): 423–433.

DOI: https://doi.org/10.1242/dmm.009092

Published: 1 July 2012

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Journal Articles

Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease

Tracey A. Rouault

Dis Model Mech (2012) 5 (2): 155–164.

DOI: https://doi.org/10.1242/dmm.009019

Published: 1 March 2012

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Journal Articles

Modeling psychiatric disorders through reprogramming

Kristen J. Brennand, Fred H. Gage

Dis Model Mech (2012) 5 (1): 26–32.

DOI: https://doi.org/10.1242/dmm.008268

Published: 1 January 2012

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Journal Articles

Studying synthetic lethal interactions in the zebrafish system: insight into disease genes and mechanisms

Vinita A. Hajeri, James F. Amatruda

Dis Model Mech (2012) 5 (1): 33–37.

DOI: https://doi.org/10.1242/dmm.007989

Published: 1 January 2012

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Journal Articles

Animal models for Gaucher disease research

Tamar Farfel-Becker, Einat B. Vitner, Anthony H. Futerman

Dis Model Mech (2011) 4 (6): 746–752.

DOI: https://doi.org/10.1242/dmm.008185

Published: 1 November 2011

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Journal Articles

Down syndrome: searching for the genetic culprits

Eva Lana-Elola, Sheona D. Watson-Scales, Elizabeth M. C. Fisher, Victor L. J. Tybulewicz

Dis Model Mech (2011) 4 (5): 586–595.

DOI: https://doi.org/10.1242/dmm.008078

Published: 1 September 2011

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Journal Articles

Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases

Joyce Lin, David J. Hackam

Dis Model Mech (2011) 4 (4): 447–456.

DOI: https://doi.org/10.1242/dmm.007252

Published: 1 July 2011

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Journal Articles

Mouse models of myeloproliferative neoplasms: JAK of all grades

Juan Li, David G. Kent, Edwin Chen, Anthony R. Green

Dis Model Mech (2011) 4 (3): 311–317.

DOI: https://doi.org/10.1242/dmm.006817

Published: 1 May 2011

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Journal Articles

Mouse models and the interpretation of human GWAS in type 2 diabetes and obesity

Roger D. Cox, Christopher D. Church

Dis Model Mech (2011) 4 (2): 155–164.

DOI: https://doi.org/10.1242/dmm.000414

Published: 1 March 2011

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Journal Articles

Mouse models of cancer as biological filters for complex genomic data

Elisa Oricchio, Andrew L. Wolfe, Jonathan H. Schatz, Konstantinos J. Mavrakis, Hans-Guido Wendel

Dis Model Mech (2010) 3 (11-12): 701–704.

DOI: https://doi.org/10.1242/dmm.006296

Published: 28 October 2010

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Journal Articles

Restoring the balance between disease and repair in multiple sclerosis: insights from mouse models

Robert H. Miller, Sharyl L. Fyffe-Maricich

Dis Model Mech (2010) 3 (9-10): 535–539.

DOI: https://doi.org/10.1242/dmm.001958

Published: 1 September 2010

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Journal Articles

Linking model systems to cancer therapeutics: the case of Mastermind

Barry Yedvobnick, Ken Moberg

Dis Model Mech (2010) 3 (9-10): 540–544.

DOI: https://doi.org/10.1242/dmm.005520

Published: 1 September 2010

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Journal Articles

Potential and pitfalls of stem cell therapy in old age

David Piccin, Cindi M. Morshead

Dis Model Mech (2010) 3 (7-8): 421–425.

DOI: https://doi.org/10.1242/dmm.003137

Published: 7 July 2010

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Journal Articles

Sweetness and light: perspectives for rodent models of type 1 diabetes

Philip R. Avner

Dis Model Mech (2010) 3 (7-8): 426–429.

DOI: https://doi.org/10.1242/dmm.004705

Published: 7 July 2010

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Journal Articles

Insights into the role of DNA methylation in disease through the use of mouse models

Melissa Conerly, William M. Grady

Dis Model Mech (2010) 3 (5-6): 290–297.

DOI: https://doi.org/10.1242/dmm.004812

Published: 28 April 2010

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NARROW

Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis

Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models

Role of resting metabolic rate and energy expenditure in hunger and appetite control: a new formulation

Obesity and psychotic disorders: uncovering common mechanisms through metabolomics

Anti-obesity drugs: past, present and future

Putting together the psoriasis puzzle: an update on developing targeted therapies

Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease

Modeling psychiatric disorders through reprogramming

Studying synthetic lethal interactions in the zebrafish system: insight into disease genes and mechanisms

Animal models for Gaucher disease research

Down syndrome: searching for the genetic culprits

Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases

Mouse models of myeloproliferative neoplasms: JAK of all grades

Mouse models and the interpretation of human GWAS in type 2 diabetes and obesity

Mouse models of cancer as biological filters for complex genomic data

Restoring the balance between disease and repair in multiple sclerosis: insights from mouse models

Linking model systems to cancer therapeutics: the case of Mastermind

Potential and pitfalls of stem cell therapy in old age

Sweetness and light: perspectives for rodent models of type 1 diabetes

Insights into the role of DNA methylation in disease through the use of mouse models

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