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Cover image
Cover Image
Cover: Macro image of an individual Drosophila melanogaster used for in vivo high-throughput screening in myotonic dystrophy type 1 (DM1). This fly model does not display eye-observable disease phenotypes but combines simultaneous expression of the disease-causing mutation and a luciferase-reporter system, which allows the reliable quantification of a DM1-linked differential splicing event (spliceosensor flies). These reporter-based flies launched a novel in vivo drug-discovery assay from well-established in vitro approaches, and allowed fast large-scale chemical screening using Drosophila melanogaster. Image kindly provided by Dr Arturo López Castel. See article by García-Alcover et al. on page 1297. - PDF Icon PDF LinkTable of contents
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Sex matters in preclinical research
DMM calls for improved inclusion, analysis and reporting of sex as a biological variable in preclinical animal modelling research. Read the full Editorial by Monica J. Justice.
Subject collection: Building advocacy into research
DMM’s new series - Building advocacy into research - features interviews, ‘The Patient’s Voice’, with patients and advocates for a range of disease types, with the aim of supporting the highest quality research for the benefit of all patients affected by disease.
Travelling Fellowships for early-career researchers
DMM and its sister journals offer Travelling Fellowships of up to £3,000 to graduate students and post-doctoral researchers wishing to make collaborative visits to other laboratories. Find out more about our Travelling Fellowships and read stories from previous grant recipients.
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
