Loss of epithelial polarity redirects Notch signaling and triggers a Xrp1 response during neoplastic growth in Drosophila by Logeay et al.
Invasive Procedure: new insights into how changes in epithelial structure can turn Notch nasty.
The WD and linker domains of ATG16L1 required for non-canonical autophagy limit lethal influenza A virus infection at epithelial surfaces by Wang et al.
Loss of non-canonical autophagy in mice increases sensitivity to influenza A virus infection by disrupting defences at the lung epithelial barrier, but not in phagocytic leukocytes.
Bariatric surgery reveals a gut-restricted TGR5 agonist that exhibits anti-diabetic effects by Chaudhari et al.
A gut check for bariatric surgery – Surgery-mediated bile acid changes improve metabolic parameters.
NINJA: an inducible genetic model for creating neoantigens in vivo by Damo et al.
A neoantigen in disguise, the NINJA system: testing the functionality of a novel genetically engineered mouse model with an inducible neoantigen construct.
Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors by Wishart et al.
Obesity and breast cancer – Collagen VI in the spotlight
Regeneration in the adult Drosophila brain by Crocker et al.
A hidden stem cell-like population found in the Drosophila brain: let's regenerate.
On-demand spatiotemporal programming of collective cell migration via bioelectric stimulation by Zajdel et al.
An electricity-based pied piper of Hamelin: moving cells on demand.
Mutational signatures are jointly shaped by DNA damage and repair by Volkova et al.
A combinatory mutational screen in C. elegans, combining 54 DNA repair mutants and 12 genotoxins, demonstrates that mutations are a result of both DNA damage and failed repair.
Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis by Barki et al.
Following your gut – using chemogenetics to understand how short chain fatty acids regulate the gut-brain axis.