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Disease Models & Mechanisms (DMM) is an Open Access biomedical research journal advancing novel insight into the mechanism, diagnosis and therapy of human disease.

DMM is committed to publishing rigorously peer-reviewed research in disease biology that has significant translational impact at the interface of basic and clinical science. Our content is freely available to our communities of basic and clinical researchers, health professionals, patients and their advocates and families. DMM is interdisciplinary in scope, and covers a diverse range of diseases. We also publish cutting-edge techniques and resources that advance the disease biology field.

DMM is led by an international team of expert research-active Editors, including Editor-in-Chief Liz Patton and Deputy Editor-in-Chief Elaine Mardis, and supported by an outstanding Editorial Advisory Board.

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DMM included in Read & Publish agreements

From 2022, DMM is included in many of the Read & Publish agreements offered by The Company of Biologists. This enables discounted or fee-free publication of an uncapped number of Research articles in DMM for corresponding authors at participating institutions (including, among others, the Max Planck Digital Library and University of California).

Read more about the ways in which DMM is working to increase accessibility for both authors and readers in an Editorial from Editor-in-Chief Liz Patton.

Call for papers for Special Issue

DMM invites you to submit your latest research for our upcoming special issue: Moving Heart Failure to Heart Success: Mechanisms, Regeneration & Therapy. This issue will be coordinated by guest editors Jeroen Bakkers (Hubrecht Institute, The Netherlands), Milena Bellin (Department of Biology, University of Padova, Italy, and Leiden University Medical Center, The Netherlands) and Ravi Karra (Duke University School of Medicine, USA).

The deadline for submitting articles to the special issue is Monday July 4 2022.

Find out more about how to submit.

New Reviews from DMM

Craniosynostosis has broad clinical manifestations and a complex aetiology. Chai et al. review studies from humans and animal models, and discuss the developmental mechanisms of craniosynostosis and potential mesenchymal stem-cell-based suture regeneration therapeutic strategies.

A new article from Champion and colleagues reviews and analyses the available preclinical models for five common neonatal diseases to direct therapeutic development in these areas of high unmet medical need.

2021 Outstanding Paper Prize winner

Meet Daniel Broder - winner of the 2021 outstanding paper prize for his paper TP53 loss initiates chromosomal instability in fallopian tube epithelial cells’.

Editor's Choice

Cao, Zhao and colleagues established zebrafish glioblastoma (GBM) xenograft models that can be used to perform genetic and biological analyses of GBMs, identify drugs that penetrate the blood–brain barrier and predict clinical sensitivity to temozolomide in GBM patients.

Read our new Special Issue - The RAS Pathway: Diseases, Therapeutics and Beyond

Journals from The Company of Biologists

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Journal of Cell Science current cover
Journal of Experimental Biology current cover
Disease Models and Mechanisms current cover
Biology Open current cover
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