... domains, including a GATA-type zinc finger through which it binds DNA. Mice in which the GATA domain of Trps1 has been deleted ( Trps1 Δ gt/ Δ gt ) have a reduced number of pelage follicles and lack vibrissae follicles postnatally. To identify the transcriptional targets of Trps1 in the developing...

... follicle cavity. Over 60% of recipient follicles produced stout emergent vibrissa fibres and some operations resulted in multiple hair production from a single follicle. Histological examination revealed new dermal papillae within large bulb structures which were sited below the level of amputation...

...Colin A. B. Jahoda ABSTRACT Adult vibrissa follicle dermal papillae have the capacity to induce hair growth and follicle formation when associated with epidermis from various sources. However, the range of conditions under which hair follicle induction will take place has not been established...

... vibrissa hair follicle regeneration wound healing dermal sheath basement membrane fibronectin laminin type IV collagen Regenerative activity is relatively rare in adult mammalian biology, therefore it is intriguing that the hair follicle, which is one of the distinguishing features...

...Kenneth A. Horne; Colin A. B. Jahoda; Roy F. Oliver ABSTRACT Retention of the capacity to induce the growth of hair by cultured adult rat vibrissa dermal papilla cells has been investigated. Small pellets of serially cultured papilla cells were implanted into the bases of the exposed follicular...