... revealed that bidirectional alterations of cAMP levels in the postsynaptic muscle cells alter the balance of GluR subtypes in a cell-autonomous manner ( Fig. 8 E). Our study thus provides new insights into the mechanism underlying synaptic plasticity by altering the balance of GluR subtypes. Most...

... component of this regulatory machinery is a retrograde signal from the postsynaptic cell that mediates the formation of synaptic connections. Synaptogenesis Activity Synaptic plasticity Neuromuscular junction Retrograde signal C. elegans Patterns of neural activity play essential roles...

... to the postsynaptic components. These findings demonstrate persistent synaptic plasticity in the rod terminals of mammalian retina during the maturational phase of late postnatal development. Compensatory synaptic growth in the rod terminals, as recorded here, can have important implications for the maintenance...