... of segment polarity genes ( engrailed, wingless, hedgehog, gooseberry distal,mirror ) and DV patterning genes ( muscle segment homeobox,intermediate neuroblast defective, ventral nervous system defective ) in the procephalic neuroectoderm and the neuroblast layer (until stage 11, when all neuroblasts...

... , and gooseberry led to dramatic increases in apoptosis in the anterior of the segment while a naked mutation resulted in a dramatic increase in the death of engrailed cells in the posterior of the segment. These results show that segment polarity gene expression is necessary for the survival of specific rows...

...Javier Capdevila; Félix Pariente; Javier Sampedro; José Luis Alonso; Isabel Guerrero ABSTRACT The product of the segment polarity gene patched is a trans-membrane protein involved in the cell communication processes that establish polarity within the embryonic segments of Drosophila . Monoclonal...

... of Biologists 1994 There is not enough information available regarding the expression and possible autonomous action of the segment polarity genes in the mesoderm. It is possible that the observed defects in muscle organization in the various mutants resulted partly from a direct mesodermal function...

...Michael J. Fietz; Jean-Paul Concordet; Robert Barbosa; Randy Johnson; Stefan Krauss; Andrew P. McMahon; Cliff Tabin; Philip W. lngham ABSTRACT The segment polarity gene hedgehog plays a central role in cell patterning during embryonic and post-embryonic development of the dipteran, Drosophila...

... at a particular phase in development, the period when segment polarity genes begin to take over the task of patterning the segment. At that time, the pair rule genes ( Nüsslein-Volhard and Wieschaus, 1980 ) have already laid down the segmented body plan. It was suggested that the prime function of pair rule genes...

...A. J. Forbes; Y. Nakano; A. M. Taylor; P. W. Ingham ABSTRACT The segment polarity genes play a fundamental role in the patterning of cells within individual body segments of the Drosophila embryo. Two of these genes wingless (wg) and hedgehog (hh) encode proteins that enter the secretory pathway...

...Jym Mohler; Kodela Vani ABSTRACT hedgehog is a segment polarity gene necessary to maintain the proper organization of each segment of the Drosophila embryo. We have identified the physical location of a number of rearrangement breakpoints associated with hedgehog mutations. The corresponding hh RNA...

...Alicia Hidalgo; Philip Ingham Intrasegmental patterning in the Drosophila embryo requires the activity of the segment polarity genes. The acquisition of positional information by cells during embryogenesis is reflected in the dynamic patterns of expression of several of these genes. In the case...