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Keywords: protein synthesis
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Journal Articles
Journal: Development
Development (2023) 150 (13): dev201492.
Published: 30 June 2023
.... These methods can enable quantitative exploration of protein synthesis and degradation mechanisms that contribute to developmental cell fate specification. Furthermore, they may support functional analysis of protein conformations and activities in single cells, and thus link protein functions to developmental...
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (7): dev172460.
Published: 8 April 2019
... not abolish, embryonic and adult myogenesis. Raptor Rictor Protein synthesis Satellite cells Muscle regeneration Rapamycin Myogenesis is a tightly controlled process that results in the formation of skeletal muscle in several distinct myogenic waves. During development, mesodermal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (1999) 126 (11): 2365–2375.
Published: 1 June 1999
... ( bonsaï ) in a homolog of the prokaryotic ribosomal protein, RPS15, causes a growth defect that is non-cell-autonomous. Our results emphasize the importance of translational regulation for the exit from quiescence. They suggest that the level of protein synthesis required for cell cycle progression varies...
Journal Articles
Journal Articles
Journal: Development
Development (1992) 116 (Supplement): 137–142.
Published: 1 April 1992
... synthesis in a mid blastula, but has become independent of it by the late blastula stage. In animal caps induced to become mesoderm, the time when protein synthesis is required for subsequent elongation immediately follows the time of induction, and is not related to developmental stage. For elongation...
Journal Articles
Journal: Development
Development (1992) 116 (Supplement): 53–63.
Published: 1 April 1992
... by comparing protein synthesis in normal and UV-irradiated embryos. About 5% of 433 labelled polypeptides detected in 2D gels were affected by UV irradiation. The most prominent protein is a 30 kDa cytoskeletal component (p30), whose synthesis is abolished by UV irradiation. p30 synthesis peaks during...
Journal Articles
Journal: Development
Development (1991) 113 (2): 561–568.
Published: 1 October 1991
.... Several specific alterations in the protein synthesis pattern of DBA/2 androgenones were observed that reflect a defect in the regulatory mechanisms that normally modulate the synthesis of these proteins between the 8-cell and blastocyst stages. These results are consistent with a model in which...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1991) 111 (1): 171–180.
Published: 1 January 1991
... the major series of changes in protein synthesis that occurs after entry into a metaphase. We conclude therefore that the mixing of the nucleoplasm and cytoplasm is not essential for the initiation or progression of the protein repro-gramming process during maturation. In addition, the experiments show...
Journal Articles
Journal Articles
Journal: Development
Development (1989) 106 (2): 263–269.
Published: 1 June 1989
...J. R. Collier ABSTRACT Two-dimensional electrophoresis of labeled proteins and hybridization of mRNAs with specific gene probes was used to demonstrate changes in protein synthesis, and the cytoplasmic control of actin maternal mRNAs during the early development of llyanassa . The isolated polar...
Journal Articles
Journal Articles
Journal: Development
Development (1987) 101 (4): 915–923.
Published: 1 December 1987
... were interested to determine whether there was any alteration to the usual maternally directed pattern of protein synthesis in a zygote after transfer of an advanced nucleus. In particular, we wanted to know whether it was possible to detect any translation products that would indicate that there had...
Journal Articles
Journal: Development
Development (1987) 100 (4): 599–609.
Published: 1 August 1987
... is that of a ‘Born’s crescent’ with a conspicuous ‘vitelline wall’ ( Pasteels, 1964 ). When oocytes are enucleated before maturation, HS has no effect on GC formation. A nuclear factor is therefore essential, as has been demonstrated in early GC formation induced by inhibitors of protein synthesis. Finally...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1987) 99 (4): 493–500.
Published: 1 April 1987
...David G. Wilkinson; Juliet A. Bailes; Janet E. Champion; Andrew P. Mcmahon The pattern of protein synthesis in 8-, 9- and 10-day post coitum (p . c . ) mouse embryos was examined by 2-D gel electrophoresis of [ 35 S]methionine-labelled proteins. Of the 600-800 polypeptides detected only one, a 14...
Journal Articles