1-20 of 118
Keywords: proliferation
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2022) 149 (11): dev199660.
Published: 10 June 2022
... cells reveals that CDC25B indirectly increases the duration of the G1 phase, possibly by preventing phosphorylation of the retinoblastoma protein. Neural stem cells Neurogenesis Proliferation Differentiation Single-cell imaging Cell cycle kinetics G1 phase Retinoblastoma protein CDC25...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (3): dev200195.
Published: 1 February 2022
...André Rosa; Wolfgang Giese; Katja Meier; Silvanus Alt; Alexandra Klaus-Bergmann; Lowell T. Edgar; Eireen Bartels-Klein; Russell T. Collins; Anna Szymborska; Baptiste Coxam; Miguel O. Bernabeu; Holger Gerhardt ABSTRACT Endothelial cell migration and proliferation are essential for the establishment...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (2): dev194407.
Published: 24 January 2022
... in bipotent Schwann cell precursors during a specific developmental window induces Mitf and represses FoxD3 to promote melanoblast cell fate at the expense of Schwann cells in limbs. Pigmentation Cell fate Determination Proliferation Mitf FoxD3 Mouse Ligue Contre le Cancer http...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev199740.
Published: 13 September 2021
...Hessel Honkoop; Phong D. Nguyen; Veronique E. M. van der Velden; Katharina F. Sonnen; Jeroen Bakkers ABSTRACT Zebrafish are excellent at regenerating their heart by reinitiating proliferation in pre-existing cardiomyocytes. Studying how zebrafish achieve this holds great potential in developing new...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (2): dev193409.
Published: 25 January 2021
.... In contrast, cartilage overgrowth and scoliosis are absent in rare viable nkx3.2 knockdown animals that lack jaw joints, supporting post-embryonic roles for Nkx3.2. Single-cell RNA-sequencing and in vivo validation reveal increased proliferation and upregulation of stress-induced pathways, including...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (11): dev190231.
Published: 11 June 2020
.... ( 2000 ). Loss of FBP function arrests cellular proliferation and extinguishes c-myc expression . EMBO J.   19 , 1034 - 1044 . 10.1093/emboj/19.5.1034 Hutvagner , G. and Simard , M. J. ( 2008 ). Argonaute proteins: key players in RNA silencing . Nat. Rev. Mol. Cell Biol.   9 , 22...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (8): dev184259.
Published: 12 April 2020
...Zhen Shi; Cindy Lim; Vuong Tran; Kairong Cui; Keji Zhao; Xin Chen ABSTRACT The Drosophila male germline stem cell (GSC) lineage provides a great model to understand stem cell maintenance, proliferation, differentiation and dedifferentiation. Here, we use the Drosophila GSC lineage to systematically...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (2): dev180695.
Published: 23 January 2020
... generation by negatively regulating oligodendrocyte precursor cell (OPC) proliferation. GDE3 inhibits OPC proliferation by stimulating ciliary neurotrophic factor (CNTF)-mediated signaling through release of CNTFRα, the ligand-binding component of the CNTF-receptor multiprotein complex, which can function...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (19): dev178632.
Published: 9 October 2019
...Raz Ben-Yair; Vincent L. Butty; Michele Busby; Yutong Qiu; Stuart S. Levine; Alon Goren; Laurie A. Boyer; C. Geoffrey Burns; Caroline E. Burns ABSTRACT Deciphering the genetic and epigenetic regulation of cardiomyocyte proliferation in organisms that are capable of robust cardiac renewal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev178087.
Published: 9 May 2019
... levels of GATAe gene expression in tubule principal cells induce uncontrolled cell proliferation, resulting in tumorous growth with associated altered expression of apoptotic and carcinogenic key genes. Furthermore, we uncover the involvement of GATAe in the maintenance of stellate cells and migration...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (3): dev170753.
Published: 1 February 2019
... is essential for cardiomyocyte proliferation and cardiogenesis. Mosaic Myc overexpression in a Mycn -deficient background shows that Myc can replace Mycn function, recovering heart development. We further show that this recovery involves the elimination of Mycn-deficient cells by cell competition. Our results...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (2): dev167643.
Published: 29 January 2019
... and highlighting JAK/STAT pathway functions in proliferation, survival and cell competition that are conserved between Drosophila and vertebrates. upd continues to be produced by niche cells in the adult testis but declines with age ( Kiger et al., 2001 ; Toledano et al., 2012 ; Tulina and Matunis, 2001...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (1): dev166595.
Published: 9 January 2019
.... Here, we study how increased cell number evolved in the vertebrate central nervous system, investigating the regulation of cell proliferation in the lamprey spinal cord. Markers of proliferation show that a ventricular progenitor zone is found throughout the lamprey spinal cord. We show that inhibition...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (13): dev161182.
Published: 2 July 2018
... that Cdc42 is required for endothelial tip cell selection, directed cell migration and filopodia formation, but dispensable for cell proliferation or apoptosis. Although the loss of Cdc42 seems generally compatible with apical-basal polarization and lumen formation in retinal blood vessels, it leads...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (11): dev160127.
Published: 11 June 2018
..., proliferation and survival of glial precursors. Both the switch from neurogenesis to gliogenesis and the subsequent glial expansion depend on Notch signaling. Taken together, lineage origins preconfigure the development of individual glial precursors with involvement of serial Notch actions in promoting...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (23): 4406–4421.
Published: 1 December 2017
... hormone 20-hydroxyecdysone (20E) in the maintenance of numerous patterning systems in vivo and in explant culture. We find that low concentrations of 20E support prolonged proliferation in explanted wing discs in the absence of insulin, incidentally providing novel insight into the hormonal regulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (23): 4462–4472.
Published: 1 December 2017
... and tissue movements during elongation. We quantify the tissue-specific contribution to axis elongation using 3D volumetric techniques, then quantify tissue-specific parameters such as cell density and proliferation. To study cell behavior at a multi-tissue scale, we used high-resolution 4D imaging...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (3): 479–486.
Published: 1 February 2017
... by cell-cell sorting analyses. However, we demonstrate that only the earlier autopod cells can adopt the host proliferation rate to permit normal morphogenesis. Therefore, our findings reveal that the ability of embryonic cells to differentially reset their intrinsic behaviours confers robustness to limb...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (23): 4509–4520.
Published: 1 December 2016
...Gewei Lian; Markus Dettenhofer; Jie Lu; Michael Downing; Anjen Chenn; Timothy Wong; Volney Sheen Actin-associated proteins regulate multiple cellular processes, including proliferation and differentiation, but the molecular mechanisms underlying these processes are unclear. Here, we report...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (13): 2398–2409.
Published: 1 July 2016
... the liver. However, its role in the brain remains unclear. Here, we provide evidence for YAP regulation of mouse neocortical astrocytic differentiation and proliferation. YAP was undetectable in neurons, but selectively expressed in neural stem cells (NSCs) and astrocytes. YAP in NSCs was required...
Includes: Supplementary data