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Keywords: patterning
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Journal Articles
Journal: Development
Development (2023) 150 (22): dev201886.
Published: 22 November 2023
... is established during kidney development. More specifically, how signals from the kidney influence vessel maturity and patterning remains poorly understood. Netrin 1 (Ntn1) is a secreted ligand that is crucial for vessel and neuronal guidance. Here, we demonstrate that Ntn1 is expressed by Foxd1 + stromal...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2023) 150 (19): dev201559.
Published: 3 October 2023
... the Fgf8a gradient curve with expression profiles of its downstream targets determines the precise input-output relationship of Fgf8a-mediated patterning. Manipulation of the extracellular Fgf8a levels alters the signaling outcome, thus establishing Fgf8a as a bona fide morphogen during zebrafish...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (18): dev201777.
Published: 25 September 2023
... of head regeneration and patterning defects in amputated tail fragments. alx-3 is required for the expression of several early wound-induced genes, including the Wnt inhibitor notum , which is required to establish anterior polarity during regeneration. Together, these findings reveal a role for alx-3...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2023) 150 (10): dev201702.
Published: 30 May 2023
...Jan A. Adelmann; Roman Vetter; Dagmar Iber ABSTRACT Tissue patterning during embryonic development is remarkably precise. Here, we numerically determine the impact of the cell diameter, gradient length and the morphogen source on the variability of morphogen gradients. We show that the positional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (9): dev200975.
Published: 3 May 2023
... and reproduction in any medium provided that the original work is properly attributed. Highlighted Article: Relative intercellular asymmetry is a crucial factor underlying the robustness of persistently directional collective cell rotations in vivo . Multicellular rotations Patterning...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (4): dev201138.
Published: 16 February 2023
... to alternating patterns (e.g. SOP selection, hair cell in the inner ear and neural stem cell maintenance), as well as processes where Notch activity is oscillatory (e.g. somitogenesis and neurogenesis in mammals). * Author for correspondence ( davidsp@tauex.tau.ac.il ) Competing interests...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2023) 150 (1): dev192476.
Published: 16 January 2023
...: This Development at a Glance article provides an overview of the genomic organization, protein structure and regulation of Hox genes and our current understanding of their roles both during and after embryogenesis. Hox gene regulation Embryonic development Patterning Transcription factor National...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (24): dev200974.
Published: 19 December 2022
... by controlling the field expansion to the pattern created by reaction-diffusion ( Iber, 2021 ; Menshykau et al., 2014 , 2019 ), while Salazar Ciudad and Jernvall have computationally reproduced the pattern of mouse teeth ( Salazar-Ciudad and Jernvall, 2010 ). These examples demonstrate that, although...
Journal Articles
Journal: Development
Development (2022) 149 (17): dev200767.
Published: 12 September 2022
... on the SHH/BMP4 signaling axis to regulate mesenchymal patterning and differentiation. Mouse embryos with conditional loss of Fgfr1 and Fgfr2 in the ureteric mesenchyme exhibited reduced mesenchymal proliferation and prematurely activated lamina propria formation at the expense of the smooth muscle cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (16): dev200539.
Published: 17 August 2022
...Qianlin Ye; Arshia Bhojwani; Jimmy K. Hu ABSTRACT During craniofacial development, the oral epithelium begins as a morphologically homogeneous tissue that gives rise to locally complex structures, including the teeth, salivary glands and taste buds. How the epithelium is initially patterned...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (12): dev200226.
Published: 23 June 2022
... patterning of cell fate decisions. These data collectively suggest that 2 h of sender-receiver contact may be sufficient for induction of low levels of mCherry, and that mCherry levels will keep increasing in receiver cells for a period of time after the loss of sender-receiver contact. This neighbour...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (7): dev200125.
Published: 30 March 2022
... at an upstream step in patterning the AP axis. Double RNAi experiments and eye regeneration assays suggest src-1 can act in parallel to at least some Wnt and FGFRL factors. Co-inhibition of src-1 with other posterior-promoting factors led to dramatic patterning changes and a reprogramming of Wnt/FGFRLs...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2022) 149 (7): dev200410.
Published: 30 March 2022
..., but during leaf development it regulates the development of distinct cell types; bundle-sheath in Arabidopsis and mesophyll in maize. In rice, SCR is implicated in stomatal patterning, but it is unknown whether this function is additional to a role in inner leaf patterning. Here, we demonstrate that two...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (5): dev199632.
Published: 9 March 2022
... this model has not been tested. Some insects, e.g. Nasonia vitripennis and Apis mellifera segment progressively, a pattern not examined in previous studies of this segmentation model, producing stripes at different times progressively through the embryo, but not from a segment addition zone. Here, we aim...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (1): dev200140.
Published: 13 January 2022
...Esther Jeong Yoon Kim; Lydia Sorokin; Takashi Hiiragi ABSTRACT Development entails patterned emergence of diverse cell types within the embryo. In mammals, cells positioned inside the embryo give rise to the inner cell mass (ICM), which eventually forms the embryo itself. Yet, the molecular basis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (15): dev186387.
Published: 3 August 2021
... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Summary: This Primer introduces micropatterning as a tool to study development and discusses what we have learnt so far with this technique. Microfabrication Patterning Self...