... oogenesis, LD accumulation coincides with actin remodeling necessary for follicle development. Loss of the LD-associated Adipose Triglyceride Lipase (ATGL) disrupts both actin bundle formation and cortical actin integrity, an unusual phenotype also seen when the prostaglandin (PG) synthase Pxt is missing...

...Travis T. Parsons; Sheila Mosallaei; Laurel A. Raftery ABSTRACT During Drosophila oogenesis, somatic follicle cells (FCs) differentiate to secrete components of the eggshell. Before secretion, the epithelium reorganizes to shape eggshell specializations, including border FC collective cell...

... mutants of nanog (M nanog ) in zebrafish, we demonstrated that Nanog tightly controls translation of maternal mRNA during oogenesis via transcriptional repression of eukaryotic translation elongation factor 1 alpha 1, like 2 ( eef1a1l2 ). Loss of maternal Nanog led to defects of egg maturation, increased...

.... A. and Rajkovic , A. ( 2006 ). Transcriptional regulation of early oogenesis: in search of masters . Hum. Reprod. Update 12 , 65 - 76 . 10.1093/humupd/dmi033 Popow , J. , Englert , M. , Weitzer , S. , Schleiffer , A. , Mierzwa , B. , Mechtler , K. , Trowitzsch , S...

...Gregory Logan; Wei-Chien Chou; Brooke M. McCartney ABSTRACT Cells reposition their nuclei for diverse specialized functions through a wide variety of cytoskeletal mechanisms. During Drosophila oogenesis, 15 nurse cells connected by ring canals to each other and the oocyte contract, ‘dumping...

... oogenesis using the model insect Drosophila melanogaster . In adult females maintained at 18°C (cold) or 29°C (warm), relative to females at the 25°C control temperature, egg production was reduced through distinct cellular mechanisms. Chronic 18°C exposure improved germline stem cell maintenance, survival...

... mouse oocyte transcription network, including reproduction and chromatin genes, through unexpected promoter localization of TAF4b at Sp/Klf- and NFY-binding sites. Transcription Oogenesis Oocytes Meiosis I TFIID TAF4b POI Fetal oocyte attrition Mouse National Institute of Child...

... ( Campbell and Tomlinson, 1999 ; Minami et al., 1999 ), which, in addition to other mechanisms, helps shape the Dpp gradient ( Affolter et al., 2001 ; Müller et al., 2003 ; O'Connor et al., 2006 ). Brk acts similarly in the ovaries starting at stage 8 of oogenesis when it is important for establishing...

...-oogenesis. Loss of Fra in the germline, but not the somatic cells of the ovary, results in the degeneration of egg chambers. Although a failure in nutrient sensing and disruptions in egg chamber polarity can result in degeneration at mid-oogenesis, these factors do not appear to be affected in fra germline...

... challenges associated with imaging and image processing. Here, we present a supervised learning approach for quantifying the growth dynamics of germline cysts during oogenesis. Our analysis uncovers growth patterns induced by the groupwise developmental dynamics among connected cells, and differential growth...

....2004.07.019 Lei , L. and Spradling , A. C. ( 2013 ). Female mice lack adult germ-line stem cells but sustain oogenesis using stable primordial follicles . Proc. Natl. Acad. Sci. USA 110 , 8585 - 8590 . 10.1073/pnas.1306189110 Li , L. , Ji , S. Y. , Yang , J. L...

...Lesley N. Weaver; Daniela Drummond-Barbosa ABSTRACT The conserved nuclear receptor superfamily has crucial roles in many processes, including reproduction. Nuclear receptors with known roles in oogenesis have been studied mostly in the context of their ovary-intrinsic requirement. Recent studies...

... is essential for development. During late stages of Drosophila melanogaster oogenesis, the small somatic follicle cells that surround the large nurse cells promote non-apoptotic nurse cell death, subsequently engulf them, and contribute to the timely removal of nurse cell corpses. Here, we identify a role...

...Anne E. Smolko; Laura Shapiro-Kulnane; Helen K. Salz ABSTRACT Maintenance of germ cell sexual identity is essential for reproduction. Entry into the spermatogenesis or oogenesis pathway requires that the appropriate gene network is activated and the antagonist network is silenced. For example...

... metabolic networks. Having spent decades generating the tools required for cell- and tissue-specific studies, our community is poised to probe the physiological, cellular and molecular mechanisms that coordinate metabolism across an entire living organism. Studies of adult Drosophila oogenesis...

...Enxiang Chen; Zhiwei Chen; Shenglong Li; Dongxu Xing; Huizhen Guo; Jianqiu Liu; Xiaocun Ji; Ying Lin; Shiping Liu; Qingyou Xia ABSTRACT Vitellogenin receptors (VgRs) play crucial roles in oogenesis by mediating endocytosis of vitellogenin and other nutrients in ovipara. We conducted small RNA...

... 2018 http://www.biologists.com/user-licence-1-1/ Summary:   wit is regulated by alleviation of Brinker repression in two evolutionarily divergent Drosophila species, in which evolutionary changes in wit expression patterns have occurred in cis . Tissue patterning Oogenesis TGFβ...

... attributed. Highlighted Article: Characterization of the developmental defects of l(3)mbt mutant ovaries shows that L(3)mbt regulates tissue-specific gene signatures to secure the identity of somatic ovarian and germline tissues. L(3)mbt Lint-1 Tissue identity Nanos Oogenesis...

... stem cells will have their residence, thereby securing progressive oogenesis and, thus, organism reproduction. References Ables , J. L. , Breunig , J. J. , Eisch , A. J. and Rakic , P. ( 2011 ). Not(ch) just development: Notch signalling in the adult brain . Nat. Rev...

... cells, maintained by Wnt signaling, form a crucial component of the stem cell niche by promoting BMP signaling and anchoring GSCs through DE-cadherin-based junctions. Drosophila Wnt signaling Germline stem cells Oogenesis Adult tissues are maintained by stem cells that self-renew...