... of Biologists 2000 Androgenetic mouse embryos X-chromosome inactivation Genomic imprinting Nuclear transplantation lacZ gene FISH Xist gene X-chromosome inactivation (X-inactivation) ( Lyon, 1961 ) in female mouse embryos first occurs in the trophectoderm of expanded blastocysts...

... 1996 transgenic nuclear transplantation FGF mesoderm neural induction Xenopus sperm gastrulation REMI The vertebrate embryo is formed by a series of inductive events that lead to the formation of different cell types, the formation of organ rudiments and the elaboration...

... , R. , Peterson , A. and Sapienza , C. ( 1989 ). Cellular mosaicism in the methylation and expression of hemizygous loci in the mouse . Genes Dev . 3 , 1669 – 1676 . 10.1101/gad.3.11.1669 McGrath , J. and Solter , D. ( 1983 ). Nuclear transplantation in the mouse...

.... 12 08 1993 © 1993 by Company of Biologists 1993 DNA methylation epigenetic modification mouse embryo nuclear transplantation In the early mouse embryo, major changes in epigenetic modifications of the genome, such as DNA methylation, occur postzygotically before a stable...

...Peter A. Lawrence; Paul Johnston ABSTRACT We report the first attempt of its kind to study genetic interactions using young Drosophila embryos that are mosaic for wildtype and mutant cells. Using nuclear transplantation we make mosaic embryos in which a patch of cells lacks a particular...

... to influence events throughout development. It is also essential that at some stage of ontogeny the specific modifications are reversed and the whole process repeated in the formation of new germ cells. Copyright © 1986 by Company of Biologists 1986 chromosomal determinants nuclear transplantation...

.... Here we use the sdh cell marker to map internal organs in mosaics made by nuclear transplantation. We confirm that oenocytes arise from the same progenitors as the adult epidermis, but that muscles and fat body have a separate (mesodermal) origin and that the precursors of epidermis and central...