1-20 of 1889
Keywords: mouse
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Journal Articles
Journal: Development
Development dev.201160.
Published: 18 November 2022
... to the lack of gene manipulation tools in SCTB. Here we aimed to generate a SCTB-specific Cre mouse and use it to determine the role of placental Fpn1. Using CRISPR/Cas9 technology, we created a Syncytin b ( Synb ) Cre line ( SynbCre ) targeting the fetal facing SCTB layer in mouse placental labyrinth...
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (22): dev201262.
Published: 16 November 2022
... ID1 is enriched in mouse basal epidermal progenitor cells and find ID1 expression to be diminished upon differentiation. In utero silencing of Id1 impairs progenitor cell proliferation, leads to precocious delamination of targeted progenitor cells and enables differentiated keratinocytes to retain...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (21): dev199931.
Published: 31 October 2022
... Competing interests The authors declare no competing or financial interests. 27 6 2021 3 10 2022 © 2022. Published by The Company of Biologists Ltd 2022 Summary: Loss of PAR3 in mouse telencephalon reveals that PAR3 regulates the transition to neurogenic divisions at early...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (21): dev200909.
Published: 31 October 2022
.... Importantly, deficits in vascular development lead to significant pediatric lung diseases, indicating a need to uncover fetal programs promoting vascular growth. To address this, we used a transgenic mouse reporter for expression of Cxcl12 , an arterial endothelial hallmark gene, and performed single-cell RNA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (21): dev200788.
Published: 25 October 2022
.... In this study, we report that deletion of Isl1 in the mouse mandibular epithelium leads to aglossia due to myoblast migration defects. Isl1 regulates the expression pattern of chemokine ligand 12 ( Cxcl12 ) in the first branchial arch through the Shh/Wnt5a cascade. Cxcl12 + mesenchymal cells in Isl1 ShhCre...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (21): dev200953.
Published: 21 October 2022
... in dentate gyrus morphogenesis. Summary: Loss of β-catenin in the embryonic mouse hem causes profoundly defective dentate gyrus morphogenesis and Cajal-Retzius migration due to disorganization of the fimbrial glial scaffold. β-Catenin Cajal-Retzius cells Dentate gyrus Dentate gyrus...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (19): dev200913.
Published: 12 October 2022
... in the mouse mammary gland. Notch3 is expressed in the luminal compartment throughout mammary gland development, but switches to basal cells with initiation of post-lactational involution. Deletion of Notch3 caused a decrease of Notch activation in luminal cells and diminished luminal progenitors at puberty...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (18): dev200654.
Published: 22 September 2022
... types to enable cardiomyocyte (CM) proliferation. How these cells interact to create growth niches is unclear. Here, we profile proliferation kinetics of cardiac endothelial cells (CECs) and CMs in the neonatal mouse heart and find that they are spatiotemporally coupled. We show that coupled myovascular...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (17): dev201074.
Published: 7 September 2022
...Agnès Dubois; Loris Vincenti; Almira Chervova; Maxim V. C. Greenberg; Sandrine Vandormael-Pournin; Déborah Bourc'his; Michel Cohen-Tannoudji; Pablo Navarro ABSTRACT Mouse embryonic stem cells have an inherent propensity to explore gene regulatory states associated with either self-renewal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (16): dev200765.
Published: 18 August 2022
... by The Company of Biologists Ltd 2022 Summary: This Review presents the intrinsic and extrinsic mechanical forces acting on the embryonic gut and their determining role in structuring the development of this organ. Biomechanics Intestine Embryo Mouse Chicken Human Université de Paris...
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (14): dev200937.
Published: 25 July 2022
... the embryonic mouse midbrain, we hypothesized that the genes expressed downstream of Gata2 could contribute to the diversification of GABAergic neuron subtypes in this brain region. Here, we show that Gata2 is required for the expression of several GABAergic lineage-specific transcription factors, including...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (14): dev200773.
Published: 25 July 2022
... ). Global quantification of tissue dynamics in the developing mouse kidney . Dev. Cell 29 , 188 - 202 . 10.1016/j.devcel.2014.02.017 Stark , K. , Vainio , S. , Vassileva , G. and McMahon , A. P. ( 1994 ). Epithelial transformation of metanephric mesenchyme in the developing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (14): dev200154.
Published: 14 July 2022
... signaling Intercellular communication Mouse Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659 Center for Molecular Medicine Cologne, University of Cologne http://dx.doi.org/10.13039/501100009983 Universität des Saarlandes http://dx.doi.org/10.13039...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (13): dev200557.
Published: 8 July 2022
...-specific gene expression. We next tested the ability of our data to provide more granular detail on cell-type annotation from equivalent populations in other model systems. Recently, Rossi et al. reported the generation of gastruloids from mouse embryonic stem cells that mimic development of cardiac...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (13): dev200448.
Published: 4 July 2022
... in the formation of V1R + /apical and V2R + /basal vomeronasal sensory neurons of rodents. Single cell RNA sequencing Vomeronasal organ Notch signaling Dll4 Neuronal dichotomy Mouse Neuronal differentiation Eunice Kennedy Shriver National Institute of Child Health and Human Development http...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2022) 149 (13): dev200432.
Published: 29 June 2022
...Xiaodun Yang; Jeffrey C. Raum; Junil Kim; Reynold Yu; Juxiang Yang; Gabriella Rice; Changhong Li; Kyoung-Jae Won; Diana E. Stanescu; Doris A. Stoffers ABSTRACT Pancreatic and duodenal homeobox 1 (PDX1) is crucial for pancreas organogenesis, yet the dynamic changes in PDX1 binding in human or mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (12): dev200419.
Published: 22 June 2022
.... Procr Endothelial progenitor Vessel initiation Fate mapping Embryonic vessel Mouse National Natural Science Foundation of China http://dx.doi.org/10.13039/501100001809 31830056 81873532 31861163006 Chinese Academy of Sciences XDA16020200 National Key Research...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (12): dev200330.
Published: 20 June 2022
... of seminiferous tubules of Prm1 +/+ , Prm1 +/− and Prm1 −/− mice ( n =4); 25 tubules per mouse were evaluated. (C) Quantification of elongating spermatids per seminiferous tubule cross-section in Prm1 +/+ , Prm1 +/− and Prm1 −/− males ( n =3). Five tubules per mouse were evaluated. (D) Hematoxylin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (12): dev199573.
Published: 16 June 2022
... and transcription in haploid male mouse germ cells. * These authors contributed equally to this work ‡ Authors for correspondence ( tangchong@bgi.com ; sunfei@ntu.edu.cn ; wei.yan@lundquist.org ; clairezhang@ntu.edu.cn ) Handling Editor: Haruhiko Koseki Competing interests The authors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (11): dev199508.
Published: 13 June 2022
... of Neurona Therapeutics, a company studying the potential therapeutic use of interneuron transplantation. 13 2 2021 17 3 2022 © 2022. Published by The Company of Biologists Ltd 2022 Summary: In mouse embryonic basal ganglia, DLX1 interacts with the NuRD components RBBP4...
Includes: Supplementary data