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Keywords: mRNA localization
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Journal Articles
Journal: Development
Development (2022) 149 (22): dev200930.
Published: 18 November 2022
...Lindsay P. Winkenbach; Dylan M. Parker; Robert T. P. Williams; Erin Osborne Nishimura ABSTRACT mRNA localization and transport are integral in regulating gene expression. In Caenorhabditis elegans embryos, the maternally inherited mRNA erm-1 ( Ezrin/Radixin/Moesin ) becomes concentrated in anterior...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2021) 148 (24): dev200027.
Published: 16 December 2021
...Cristina Tocchini; Michèle Rohner; Laurent Guerard; Poulomi Ray; Stephen E. Von Stetina; Susan E. Mango ABSTRACT mRNA localization is an evolutionarily widespread phenomenon that can facilitate subcellular protein targeting. Extensive work has focused on mRNA targeting through ‘zip-codes’ within...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (17): dev198788.
Published: 9 September 2021
... portion of the 3′UTR of orb2 impairs male fertility as a result of mislocalization of orb2 mRNA and Orb2 protein in the spermatids, confirming its importance for proper spermatogenesis. CPEB Orb2 3′UTR mRNA localization Spermatogenesis Russian Science Foundation http://dx.doi.org...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (13): dev186817.
Published: 8 July 2020
... lineage. By uncoupling translation from mRNA localization, we untangled a long-standing question: Are mRNAs directed to P granules to be translationally repressed, or do they accumulate there as a consequence of this repression? We found that translational repression preceded P granule localization...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (22): dev164657.
Published: 22 November 2018
... granule mRNAs that contributes to homotypic clustering. Our results suggest that mRNA localization signal complexity may be a feature required by the targeting and self-recruitment mechanism that drives germ plasm mRNA localization. © 2018. Published by The Company of Biologists Ltd 2018 http...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev161786.
Published: 7 September 2018
... Maternal mRNAs Metabolism Mouse spermatogenesis mRNA localization mRNA stability piRNAs PIWI proteins Regeneration Stem cells Piwi-interacting RNAs (piRNAs) are a class of small 21-32 nucleotide long non-coding RNAs present in animals ranging from sponges to humans. Like other small RNAs...
Journal Articles
Journal: Development
Development (2011) 138 (21): 4661–4671.
Published: 1 November 2011
... networks. In this study, we have identified a novel gene, CG43162, that regulates mRNA localization during oogenesis and also affects bristle development. We also showed that the Drosophila gene javelin-like, which was identified based on its bristle phenotype, is an allele of the CG43162 gene. We...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (16): 3431–3440.
Published: 15 August 2011
...Kristina S. Sinsimer; Roshan A. Jain; Seema Chatterjee; Elizabeth R. Gavis Asymmetric mRNA localization is an effective mechanism for establishing cellular and developmental polarity. Posterior localization of oskar in the Drosophila oocyte targets the synthesis of Oskar to the posterior, where...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (6): 1087–1092.
Published: 15 March 2011
...-terminal tail are not clear. To address this, we studied the effects of tail mutations on mitochondria transport, determinant mRNA localization and cytoplasmic streaming in Drosophila . Our results show that two biochemically defined elements of the tail – the ATP-independent microtubule-binding sequence...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (5): 973–982.
Published: 1 March 2008
...-acting nanos mRNA localization factor. † Author for correspondence (e-mail: lgavis@princeton.edu ) * Present address: Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA 18 12 2007 © 2008. 2008 Drosophila hnRNP mRNA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (8): 1467–1475.
Published: 15 April 2006
... in mRNA localization and helps to link microtubule minus-ends to the oocyte cortex, a novel function of the IKK family. * Author for correspondence (e-mail: k-anderson@ski.mskcc.org ) 9 2 2006 © 2006. 2006 ik2 IκB kinases mRNA localization Oogenesis Dynein-based...
Journal Articles
Journal: Development
Development (2004) 131 (9): 1949–1958.
Published: 1 May 2004
... ) mRNA localization and protein accumulation( Kelley, 1993 ; Norvell et al., 1999 ). All Drosophila hnRNPs identified so far have structural similarities to human hnRNP A/B proteins ( Dreyfuss et al.,1993 ). Sqd contains the common hnRNP structural features( Krecic and Swanson, 1999 ; Dreyfuss et al...
Journal Articles
Journal: Development
Development (2002) 129 (2): 517–526.
Published: 15 January 2002
... of germline clones of a rab11 partial loss-of-function mutation reveal a requirement for Rab11 in endocytic recycling and in the organization of posterior membrane compartments. Such analyses also reveal a requirement for Rab11 in the organization of microtubule plus ends and osk mRNA localization...
Journal Articles
Journal: Development
Development (2001) 128 (16): 3169–3177.
Published: 15 August 2001
..., negatively regulated by K(10) . Orb Drosophila DER signaling pathway gurken mRNA localization To provide further evidence that the level of Orb protein accumulation is close to that of wild type in the double mutant, we probed western blots of ovary extracts. The results are shown in Fig...