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Keywords: mRNA
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Journal Articles
Journal: Development
Development (2010) 137 (8): 1305–1314.
Published: 15 April 2010
... that nuclear-associated P granules provide a perinuclear compartment where newly exported mRNAs are collected prior to their release to the general cytoplasm. First, we show that mRNA export factors are highly enriched at the NPCs associated with P granules. Second, we discovered that the expression of high...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (1999) 126 (17): 3857–3867.
Published: 1 September 1999
... systems and transcription factors not previously reported in early sea urchin embryos, including components of Notch and TGF signal transduction pathways. As expected from earlier kinetic analyses of the embryo mRNA populations, no very prevalent protein-coding species were encountered; the most highly...
Journal Articles
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Journal Articles
Journal: Development
Development (1993) 117 (2): 641–655.
Published: 1 February 1993
... blots, we find evidence for two Psc mRNAs and, on western blots, we find evidence for two Psc proteins that are altered either in abundance or size in Psc mutants. The Psc protein accumulates in all regions of the embryo and also in many tissues in a variety of developmental stages. In all cases...
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Journal Articles
Journal: Development
Development (1991) 111 (1): 105–115.
Published: 1 January 1991
... levels of IGF-I mRNA were found in the olfactory bulb and in discrete neurons of the cranial sensory ganglia, notably in the trigeminal ganglion, as early as 13 days of gestation, in the pineal primordium of 18 day old fetuses, and in discrete groups of cells in the cochlear epithelium located laterally...
Journal Articles
Journal: Development
Development (1991) 111 (1): 191–196.
Published: 1 January 1991
... and immunofluorescence histochemistry on selected stages of embryonic chick tibiotarsi. The data show that mRNA for type X collagen appears at or about the time that we detect the first appearance of the protein. This result is incompatible with translational regulation, which would require accumulation of the mRNA...
Journal Articles
Journal: Development
Development (1990) 110 (3): 823–837.
Published: 1 November 1990
... lacking the A chain. We have here studied the occurrence of the isoforms during mouse organogenesis. In all tissues studied, the A chain mRNA and polypeptide were more weakly expressed than those of the B chains. Laminin A chain polypeptides showed a much more restricted tissue distribution than the B...
Journal Articles
Journal: Development
Development (1990) 110 (3): 955–962.
Published: 1 November 1990
... rapidly in stage IV oocytes than in previtellogenic stage I+II oocytes. Quantitative Northern analysis showed that ornithine decarboxylase mRNA is abundant in oocytes (about 8×l0 8 transcripts/cell) and this number does not significantly change during oogenesis. Polysome analysis showed that this mRNA...
Journal Articles
Journal Articles
Journal: Development
Development (1990) 109 (2): 473–481.
Published: 1 June 1990
... hybridization experiments with mouse embryos and adult tissues, we first detected C/EBP mRNA in hepatocytes at the 13th gestational day, when no other cell types give detectable signals and thus by this test C/EBP is, at least in the embryo, a ‘liver-specific’ factor. Only trace amounts of C/EBP were seen...
Journal Articles
Journal: Development
Development (1990) 109 (1): 67–73.
Published: 1 May 1990
... hybridization (ISH) in the developing rat. Expression occurs in extra-embryonic membranes at the time of IGF-n mRNA induction and later at paracrine/ autocrine sites of IGF-II action (skeletal muscle and perichondrium) in the embryo. Highest levels of receptor mRNA occur in heart and major vessels. Postnatally...
Journal Articles
Journal: Development
Development (1989) 106 (2): 263–269.
Published: 1 June 1989
...J. R. Collier ABSTRACT Two-dimensional electrophoresis of labeled proteins and hybridization of mRNAs with specific gene probes was used to demonstrate changes in protein synthesis, and the cytoplasmic control of actin maternal mRNAs during the early development of llyanassa . The isolated polar...
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Journal Articles
Journal: Development
Development (1988) 104 (1): 29–39.
Published: 1 September 1988
... histochemistry) and for Northern blotting. IGF-II mRNA is strongly expressed in liver, skeletal muscle, perichondrium, leptomeninges and choroid plexus of the newborn. Demonstrable levels fall dramatically in the liver at 18-20 days postnatally but persist for longer periods in muscle and remain undiminished...
Journal Articles
Journal: Development
Development (1988) 103 (1): 59–67.
Published: 1 May 1988
...Patrick H. Krone; John J. Heikkila Heat-induced accumulation of hsp 30 mRNA (1·1 kb) during early development of Xenopus laevis was first detectable at the tailbud stage (stage 30–34). This contrasts with heat-induced accumulation of hsp 70 mRNA (2·7 kb) and ubiquitin mRNA (size range = 1·7–3·1 kb...