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Keywords: hunchback
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Journal Articles
Journal: Development
Development (2021) 148 (18): dev196121.
Published: 15 April 2021
...Daisy J. Vinter; Caroline Hoppe; Thomas G. Minchington; Catherine Sutcliffe; Hilary L. Ashe ABSTRACT The Hunchback (Hb) transcription factor is crucial for anterior-posterior patterning of the Drosophila embryo. The maternal hb mRNA acts as a paradigm for translational regulation due to its...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (7): dev175570.
Published: 5 April 2019
... of birth. We show that the U1-U5 neurons project axons sequentially, followed by sequential dendrite extension. We misexpressed the earliest temporal transcription factor, Hunchback, to create ‘ectopic’ U1 neurons with an early intrinsic temporal identity but later birth-order. These ectopic U1 neurons...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (22): 4366–4374.
Published: 15 November 2014
... Crustacean cardioactive peptide (CCAP) . There are two types of CCAP neurons: interneurons and efferent neurons. We found that both are specified during the Hunchback temporal window of neuroblast 3-5, but are not sibling cells. Further, this temporal window generates two ganglion mother cells that give rise...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (9): 1421–1430.
Published: 1 May 2010
...Khoa D. Tran; Michael R. Miller; Chris Q. Doe The Hunchback/Ikaros family of zinc-finger transcription factors is essential for specifying the anterior/posterior body axis in insects, the fate of early-born pioneer neurons in Drosophila , and for retinal and immune development in mammals. Hunchback...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (21): 3491–3499.
Published: 1 November 2008
...Khoa D. Tran; Chris Q. Doe Neurogenesis in Drosophila and mammals requires the precise integration of spatial and temporal cues. In Drosophila , embryonic neural progenitors (neuroblasts) sequentially express the transcription factors Hunchback, Kruppel, Pdm1/Pdm2 (Pdm) and Castor as they generate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (3): 429–437.
Published: 1 February 2006
... is specified by the transient expression of the transcription factor Hunchback. When reaching the next temporal identity, this expression is switched off in the neuroblasts by seven up ( svp ) in a mitosis-dependent manner, but is maintained in their progeny (ganglion mother cells). We show that svp mRNA...
Journal Articles
Journal: Development
Development (2005) 132 (16): 3705–3715.
Published: 15 August 2005
... products to direct axial patterning than do Drosophila embryos. In Drosophila , anterior axial patterning is largely established by bicoid , a rapidly evolving maternal-effect gene, working with hunchback , which is expressed both maternally and zygotically. Here,we focus on a comparative analysis...
Journal Articles
Journal: Development
Development (2005) 132 (9): 2081–2092.
Published: 1 May 2005
... is required for activation of the gap genes hunchback and Krüppel . Given the large RNAi deletion phenotype and its regulation of hunchback and Krüppel, even-skipped seems to act as an über-gap gene in Oncopeltus , indicating that it may have both upstream and downstream roles in segmentation...
Journal Articles
Journal: Development
Development (2005) 132 (9): 2069–2079.
Published: 1 May 2005
... germ insect, Gryllus bimaculatus ( Gb ). Here, we have focused on its hunchback ortholog( Gb ' hb ), because Drosophila hb functions as a gap gene during anterior segmentation, referred as a canonical function. Gb'hb is expressed in a gap pattern during the early stages of embryogenesis, and later...
Journal Articles
Journal: Development
Development (2004) 131 (7): 1515–1527.
Published: 1 April 2004
... of the homolog of the Drosophila gap gene hunchback in an intermediate germ insect, the milkweed bug, Oncopeltus fasciatus . We find that Oncopeltus hunchback ( Of'hb ) is expressed in two phases,first in a gap-like domain in the blastoderm and later in the posterior growth zone during germband elongation...
Journal Articles
Journal: Development
Development (2002) 129 (4): 1027–1036.
Published: 15 February 2002
... Hunchback (Hb) is expressed in the early sublineage of NB7-3, which consists of the early NB and the first GMC (GMC7-3a) and its progeny (EW1 and GW), prompted us to investigate its possible role in NB7-3 lineage development. Our analysis revealed that loss of hb results in a lack of the normally Hb...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3435–3444.
Published: 15 September 2001
... , 201 -213. Patel, N. H., Ball, E. E. and Goodman, C. S. ( 1992 ). Changing role of even-skipped during the evolution of insect pattern formation. Nature 357 , 339 -342. Patel, N. H., Hayward, D. C., Lall, S., Gleich, N., DiPietro, D. and Ball, E. ( 2001 ). Grasshopper hunchback...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3459–3472.
Published: 15 September 2001
...-rule genes such as even-skipped are not conserved between these species. This might suggest that the factors upstream of pair-rule gene expression are not conserved across insect species. We find that, despite this, many aspects of the expression of the Drosophila gap gene hunchback are shared with its...