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Fan-Suo Geng, Leila Abbas, Sarah Baxendale, Celia J. Holdsworth, A. George Swanson, Krasimir Slanchev, Matthias Hammerschmidt, Jacek Topczewski, Tanya T. Whitfield
Development (2013) 140 (21): 4362–4374.
Published: 1 November 2013
... at abnormally high levels into late larval stages. The lau mutations disrupt gpr126 , an adhesion class G protein-coupled receptor gene. Expression of gpr126 is similar to that of sox10, an ear and neural crest marker, and is partially dependent on sox10 activity. Fusion of canal projections and downregulation...
Includes: Supplementary data
Development (2011) 138 (13): 2673–2680.
Published: 1 July 2011
... that control myelination are incompletely understood. In this study, we show that Gpr126 is essential for myelination and other aspects of peripheral nerve development in mammals. A mutation in Gpr126 causes a severe congenital hypomyelinating peripheral neuropathy in mice, and expression of differentiated...
Includes: Multimedia, Supplementary data