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Keywords: fused
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Journal Articles
Journal: Development
Development (2018) 145 (24): dev166850.
Published: 12 December 2018
... domain of Fused (Fu) and highly activate its kinase activity. We further show that this binding induces changes in the association of Fu protein with the HSC and increases the proximity of the Fu catalytic domain to its substrate, the Costal2 kinesin. We propose a new model in which, depending...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (5): 931–942.
Published: 1 March 2015
... transcription factors, Drosophila Cubitus interruptus (Ci) and mammalian Gli proteins. Cos2 and Kif7 are also necessary for full activation of full-length Ci-155 and Gli transcription factors in response to Hh proteins. Here, we use classical fused alleles and transgenic Cos2 products deficient for Fused (Fu...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (1993) 119 (Supplement): 115–124.
Published: 1 December 1993
... by the activity of four other segment polarity genes, patched, fused, costal-2 and cubitus interruptus. The results of our genetic epistatsis analysis together with the molecular structures of the products of these genes where known, suggest a pathway of interactions leading from reception of the hh -encoded...