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Keywords: eyeless
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Journal Articles
Journal: Development
Development (2018) 145 (15): dev163329.
Published: 2 August 2018
...) severe retinal defects accompany its loss; (3) Pax6 genes have the ability to substitute for one another across the animal kingdom; and (4) Pax6 genes are capable of inducing ectopic eye/lens in flies and mammals. Many roles of Pax6 were first elucidated in Drosophila through studies of the gene eyeless...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (24): 4881–4889.
Published: 15 December 2006
...Tianyi Zhang; Swati Ranade; Chuan Qi Cai; Christopher Clouser; Francesca Pignoni During eye development, the selector factors of the Eyeless/Pax6 or Retinal Determination (RD) network control specification of organ-type whereas the bHLH-type proneural factor Atonal drives neurogenesis. Although...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (12): 2771–2782.
Published: 15 June 2005
...Tobias Pauli; Makiko Seimiya; Jorge Blanco; Walter J. Gehring In Drosophila , the sine oculis ( so ) gene is important for the development of the entire visual system, including Bolwig's organ, compound eyes and ocelli. Together with twin of eyeless , eyeless , eyes absent and dachshund , so...
Journal Articles
Journal: Development
Development (2003) 130 (13): 2939–2951.
Published: 1 July 2003
... cause reduction or absence of the eye. Similar to the Pax6 eyeless ( ey ) gene, ectopic expression of eyg induces extra eye formation, but at sites different from those induced by ey . Several lines of evidence suggest that eyg and ey act cooperatively: (1) eyg expression is not regulated by ey , nor...
Journal Articles
Journal: Development
Development (2002) 129 (4): 1015–1026.
Published: 15 February 2002
...Jesper Kronhamn; Erich Frei; Michael Daube; Renjie Jiao; Yandong Shi; Markus Noll; Åsa Rasmuson-Lestander The two Pax6 gene homologs eyeless and twin of eyeless play decisive early roles in Drosophila eye development. Strong mutants of twin of eyeless or of eyeless are headless, which suggests...
Journal Articles
Journal: Development
Development (2001) 128 (17): 3307–3319.
Published: 1 September 2001
... by Eyeless and generates headless flies, which suggests that Eyeless is necessary for initiating cell proliferation and development of both the eye and antennal disc. Interference occurs through a block in the cell cycle that for some ectopic transcription factors is overcome by D-CycE or D-Myc. Late ectopic...